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CBS antibody (N-Term)

Name: CBS antibody (N-Term)
SKU: ABIN1881141
Price: 429 USD
Availability: InStock

CBS Reactivity: Human, Mouse WB, IF, IHC (p), FACS Host: Rabbit Polyclonal RB22961 unconjugated

Western blot analysis of CBS Antibody (N-term) (ABIN1881141 and ABIN2841140) in mouse kidney tissue and Ramos cell line lysates (35 μg/lane). (CBS antibody (N-Term))

Confocal immunofluorescent analysis of CBS Antibody (N-term) (ABIN1881141 and ABIN2841140) with 293 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). (CBS antibody (N-Term))

Western blot analysis of CBS (arrow) using rabbit polyclonal CBS Antibody (N-term) (ABIN1881141 and ABIN2841140). (CBS antibody (N-Term))

CBS Antibody (N-term) (ABIN1881141 and ABIN2841140) flow cytometric analysis of Ramos cells (bottom histogram) compared to a negative control cell (top histogram). (CBS antibody (N-Term))

FACS

CBS Antibody (N-term) (ABIN1881141 and ABIN2841140) IHC analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. (CBS antibody (N-Term))

IHC (p)

5 images

(2 references)

Catalog No. ABIN1881141

Datasheet as PDF

Target See all CBS Antibodies

CBS (Cystathionine-beta-Synthase (CBS))
Binding Specificity
15

9

6

6

4

4

2

2

2

2

1

1

1

1

1

1
AA 104-133, N-Term
Reactivity
54

40

12

4

2

2

2

2

1

1

1

1

1
Human, Mouse
Host
65

9
Rabbit
Compatible Secondaries
Clonality
59

15
Polyclonal
Conjugate
39

6

6

4

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This CBS antibody is un-conjugated
Application
56

31

17

14

14

13

13

7

5

5

3

2

2

1

1

1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen

This CBS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-133 amino acids from the N-terminal region of human CBS.

Clone

RB22961

Isotype

Ig Fraction

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Discover our top product CBS Primary Antibody
anti-Cystathionine-beta-Synthase (CBS) (AA 1-100) antibody
CBS Reactivity: Human WB, ELISA, IHC (p), IP, RNAi Host: Mouse Monoclonal 3E1 unconjugated

anti-Cystathionine-beta-Synthase (CBS) (AA 252-551) antibody
CBS Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated

anti-Cystathionine-beta-Synthase (CBS) (AA 301-330) antibody
CBS Reactivity: Human, Mouse, Rat WB, IF, IHC (p), FACS Host: Rabbit Polyclonal RB21183 unconjugated

anti-Cystathionine-beta-Synthase (CBS) (AA 1-100) antibody
CBS Reactivity: Human WB, ELISA, IF, IHC (p) Host: Mouse Monoclonal 6A9 unconjugated

anti-Cystathionine-beta-Synthase (CBS) (N-Term) antibody
CBS Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Saccharomyces cerevisiae, Zebrafish (Danio rerio) WB, IHC Host: Rabbit Polyclonal unconjugated

anti-Cystathionine-beta-Synthase (CBS) (AA 1-413) antibody
CBS Reactivity: Human WB, ELISA, IHC, IF, IP Host: Rabbit Polyclonal unconjugated

anti-Cystathionine-beta-Synthase (CBS) antibody
KO Validated CBS Reactivity: Human WB, IF, IHC (p), IP, ICC Host: Rabbit Polyclonal unconjugated

anti-Cystathionine-beta-Synthase (CBS) antibody
CBS Reactivity: Human WB, IHC, IF Host: Rabbit Monoclonal unconjugated

anti-Cystathionine-beta-Synthase (CBS) (AA 1-551) antibody
CBS Reactivity: Human WB, ELISA Host: Mouse Polyclonal unconjugated

anti-Cystathionine-beta-Synthase (CBS) (AA 1-551) antibody
CBS Reactivity: Human WB Host: Rabbit Polyclonal unconjugated

Application Notes

IF: 1:10~50. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions

For Research Use only
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C,-20 °C

Expiry Date

6 months
Lee, Feliers, Mariappan, Sataranatarajan, Choudhury, Gorin, Kasinath: "Tadalafil Integrates Nitric Oxide-Hydrogen Sulfide Signaling to Inhibit High Glucose-induced Matrix Protein Synthesis in Podocytes." in: The Journal of biological chemistry, Vol. 290, Issue 19, pp. 12014-26, (2015) (PubMed).

Lee, Mariappan, Feliers, Cavaglieri, Sataranatarajan, Abboud, Choudhury, Kasinath: "Hydrogen sulfide inhibits high glucose-induced matrix protein synthesis by activating AMP-activated protein kinase in renal epithelial cells." in: The Journal of biological chemistry, Vol. 287, Issue 7, pp. 4451-61, (2012) (PubMed).
Target

CBS (Cystathionine-beta-Synthase (CBS))

Alternative Name

CBS (CBS Products)

Synonyms

hip4 antibody, GB12529 antibody, CBS antibody, DDBDRAFT_0189727 antibody, DDBDRAFT_0191292 antibody, DDB_0189727 antibody, DDB_0191292 antibody, cbs antibody, AI047524 antibody, AI303044 antibody, HIP4 antibody, cb442 antibody, wu:fb37g05 antibody, wu:fm61c07 antibody, wu:fq06c06 antibody, zgc:113704 antibody, cystathionine-beta-synthase L homeolog antibody, cystathionine-beta-synthase antibody, cystathionine beta-synthase antibody, cystathionine beta-synthase CBS antibody, cystathionine beta synthase antibody, cystathionine-beta-synthase S homeolog antibody, cystathionine-beta-synthase b antibody, cbs.L antibody, cbs antibody, Cbs antibody, CBS antibody, CNA06170 antibody, Tb11.02.5400 antibody, cysB antibody, LOC100635325 antibody, cbs.S antibody, cbsb antibody

Background

CBS acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. This protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria.

Molecular Weight

60587

NCBI Accession

NP_000062, NP_001171479, NP_001171480

UniProt

P35520