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ATG4B antibody (AA 250-290)

ATG4B Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1881082
  • Target See all ATG4B Antibodies
    ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))
    Binding Specificity
    • 21
    • 17
    • 15
    • 8
    • 8
    • 7
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 250-290
    Reactivity
    • 108
    • 50
    • 26
    • 8
    • 7
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Human
    Host
    • 106
    • 4
    Rabbit
    Clonality
    • 105
    • 5
    Polyclonal
    Conjugate
    • 49
    • 7
    • 7
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ATG4B antibody is un-conjugated
    Application
    • 84
    • 32
    • 23
    • 20
    • 18
    • 17
    • 13
    • 13
    • 11
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB)
    Predicted Reactivity
    B, C, Zf, M
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This ATG4B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 250-290 amino acids from the Central region of human ATG4B.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product ATG4B Primary Antibody
  • Application Notes
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Expiry Date
    6 months
  • Kabeya, Mizushima, Yamamoto, Oshitani-Okamoto, Ohsumi, Yoshimori: "LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation." in: Journal of cell science, Vol. 117, Issue Pt 13, pp. 2805-12, (2004) (PubMed).

  • Target
    ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))
    Alternative Name
    ATG4B (ATG4B Products)
    Background
    Cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes.
    Molecular Weight
    44294
    NCBI Accession
    NP_037457, NP_847896
    UniProt
    Q9Y4P1
    Pathways
    Autophagy
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