This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This AMPH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 140-168 amino acids from the Central region of human AMPH.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Expiry Date
6 months
He, Wu, Wang, Yang, Liao, Zhang: "Toward quantitative characterization of the binding profile between the human amphiphysin-1 SH3 domain and its peptide ligands." in: Amino acids, Vol. 38, Issue 4, pp. 1209-18, (2010) (PubMed).
Liu, He, Yang, Xu: "Applying chemometrics approaches to model and predict the binding affinities between the human amphiphysin SH3 domain and its peptide ligands." in: Protein and peptide letters, Vol. 17, Issue 2, pp. 246-53, (2010) (PubMed).
Zhou, Tian, Chen, Shang: "Modeling and prediction of binding affinities between the human amphiphysin SH3 domain and its peptide ligands using genetic algorithm-Gaussian processes." in: Biopolymers, Vol. 90, Issue 6, pp. 792-802, (2008) (PubMed).
Hou, Zhang, Case, Wang: "Characterization of domain-peptide interaction interface: a case study on the amphiphysin-1 SH3 domain." in: Journal of molecular biology, Vol. 376, Issue 4, pp. 1201-14, (2008) (PubMed).
This gene encodes a protein associated with the cytoplasmic surface of synaptic vesicles. A subset of patients with stiff-man syndrome who were also affected by breast cancer are positive for autoantibodies against this protein. Alternate splicing of this gene results in two transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences have not been determined. A pseudogene of this gene is found on chromosome 11.