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AKTIP antibody (C-Term)

AKTIP Reactivity: Human WB Host: Rabbit Polyclonal RB38675 unconjugated
Catalog No. ABIN1881052
  • Target See all AKTIP Antibodies
    AKTIP (AKT Interacting Protein (AKTIP))
    Binding Specificity
    • 30
    • 11
    • 7
    • 7
    • 6
    • 2
    • 1
    AA 262-288, C-Term
    Reactivity
    • 34
    • 31
    • 24
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 58
    • 6
    Rabbit
    Clonality
    • 61
    • 3
    Polyclonal
    Conjugate
    • 16
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This AKTIP antibody is un-conjugated
    Application
    • 53
    • 26
    • 26
    • 26
    • 6
    • 6
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Predicted Reactivity
    C, Pr, M, Rat
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This AKTIP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 262-288 amino acids from the C-terminal region of human AKTIP.
    Clone
    RB38675
    Isotype
    Ig Fraction
    Top Product
    Discover our top product AKTIP Primary Antibody
  • Application Notes
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Expiry Date
    6 months
  • Quaye, Dafou, Ramus, Song, Gentry-Maharaj, Maharaj, Notaridou, Hogdall, Kjaer, Christensen, Hogdall, Easton, Jacobs, Menon, Pharoah, Gayther: "Functional complementation studies identify candidate genes and common genetic variants associated with ovarian cancer survival." in: Human molecular genetics, Vol. 18, Issue 10, pp. 1869-78, (2009) (PubMed).

    Xu, Sowa, Chen, Li, Gygi, Harper: "An FTS/Hook/p107(FHIP) complex interacts with and promotes endosomal clustering by the homotypic vacuolar protein sorting complex." in: Molecular biology of the cell, Vol. 19, Issue 12, pp. 5059-71, (2008) (PubMed).

    Lamesch, Li, Milstein, Fan, Hao, Szabo, Hu, Venkatesan, Bethel, Martin, Rogers, Lawlor, McLaren, Dricot, Borick, Cusick, Vandenhaute, Dunham, Hill, Vidal: "hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes." in: Genomics, Vol. 89, Issue 3, pp. 307-15, (2007) (PubMed).

  • Target
    AKTIP (AKT Interacting Protein (AKTIP))
    Alternative Name
    AKTIP (AKTIP Products)
    Synonyms
    FT1 antibody, FTS antibody, cb798 antibody, fts antibody, zgc:77699 antibody, fts-A antibody, aktip antibody, fts-B antibody, MGC133931 antibody, AL023020 antibody, Fif antibody, Ft antibody, Ft1 antibody, Fts antibody, AKT interacting protein antibody, akt interacting protein antibody, AKT interacting protein L homeolog antibody, AKT interacting protein S homeolog antibody, thymoma viral proto-oncogene 1 interacting protein antibody, AKTIP antibody, aktip antibody, aktip.L antibody, aktip.S antibody, Aktip antibody
    Background
    The mouse homolog of this gene produces fused toes and thymic hyperplasia in heterozygous mutant animals while homozygous mutants die in early development. This gene may play a role in apoptosis as these morphological abnormalities are caused by altered patterns of programmed cell death. The protein encoded by this gene is similar to the ubiquitin ligase domain of other ubiquitin-conjugating enzymes but lacks the conserved cysteine residue that enables those enzymes to conjugate ubiquitin to the target protein. This protein interacts directly with serine/threonine kinase protein kinase B (PKB)/Akt and modulates PKB activity by enhancing the phosphorylation of PKB's regulatory sites. Alternative splicing results in two transcript variants encoding the same protein.
    Molecular Weight
    33128
    NCBI Accession
    NP_001012398, NP_071921
    UniProt
    Q9H8T0
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