ACSL1 antibody (C-Term)

Catalog No. ABIN1881044

Product Details anti-ACSL1 Antibody

Target: ACSL1 (Acsl1) (Acyl-CoA Synthetase Long-Chain Family Member 1 (Acsl1))

Binding Specificity: AA 505-533, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACSL1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ACSL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 505-533 amino acids from the C-terminal region of human ACSL1.

Clone: RB42775

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-ACSL1 antibody (ABIN1881044)

Phillips, Goumidi, Bertrais, Field, Cupples, Ordovas, Defoort, Lovegrove, Drevon, Gibney, Blaak, Kiec-Wilk, Karlstrom, Lopez-Miranda, McManus, Hercberg, Lairon, Planells, Roche: "Gene-nutrient interactions with dietary fat modulate the association between genetic variation of the ACSL1 gene and metabolic syndrome." in: Journal of lipid research, Vol. 51, Issue 7, pp. 1793-800, (2010) (PubMed).

Lu, Dollé, Imholz, van t Slot, Verschuren, Wijmenga, Feskens, Boer: "Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations." in: Journal of lipid research, Vol. 49, Issue 12, pp. 2582-9, (2008) (PubMed).

Mashek, Bornfeldt, Coleman, Berger, Bernlohr, Black, DiRusso, Farber, Guo, Hashimoto, Khodiyar, Kuypers, Maltais, Nebert, Renieri, Schaffer, Stahl, Watkins, Vasiliou, Yamamoto: "Revised nomenclature for the mammalian long-chain acyl-CoA synthetase gene family." in: Journal of lipid research, Vol. 45, Issue 10, pp. 1958-61, (2004) (PubMed).

Target Details for ACSL1

Target: ACSL1 (Acsl1) (Acyl-CoA Synthetase Long-Chain Family Member 1 (Acsl1))

Alternative Name: ACSL1 (Acsl1 Products)

Background: The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. [provided by RefSeq].

Molecular Weight: 77943

NCBI Accession: NP_001986

UniProt: P33121

Pathways: Regulation of Lipid Metabolism by PPARalpha