BRCC3 antibody (AA 7-148)

Catalog No. ABIN1866942

Product Details anti-BRCC3 Antibody

Target: BRCC3 (BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3))

Binding Specificity: AA 7-148

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BRCC3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Specificity: The antibody is a rabbit polyclonal antibody raised against BRCC3. It has been selected for its ability to recognize BRCC3 in immunohistochemical staining and western blotting.

Purification: Antigen-specific affinity chromatography

Immunogen: BRCC3 (Gln7-Gly148)

Isotype: IgG

Application Details

Application Notes:

• Western blotting: 1:50-400 Immunocytochemistry in formalin fixed cells: 1:50-500 Immunohistochemistry in formalin fixed frozen section: 1:50-500 Immunohistochemistry in paraffin section: 1:10-100 Enzyme-linked Immunosorbent Assay: 1:100-1:5000 Optimal working dilutions must be determined by end user.

Comment:

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, pH 7.4, containing 0.02 % Sodium azide, 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: 4 °C

Storage Comment: Store at 2-8 °C for one month. Aliquot and store at -80 °C for 12 months.

Expiry Date: 12 months

Target Details for BRCC3

Target: BRCC3 (BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3))

Alternative Name: BRCA1/BRCA2 Containing Complex Subunit 3 (BRCC3 Products)

Synonyms: CXorf53 antibody, BRCC3 antibody, xtp1 antibody, brcc3 antibody, BRCC36 antibody, brcc36 antibody, C6.1A antibody, BRCA1/BRCA2-containing complex subunit 3 antibody, DEP domain containing 1B antibody, BRCA1/BRCA2-containing complex, subunit 3 antibody, BRCA1/BRCA2-containing complex subunit 3 L homeolog antibody, BRCC3 antibody, depdc1b antibody, brcc3 antibody, Brcc3 antibody, brcc3.L antibody

Background: Alternative Names: C6.1A, BRCC36, C6.1A, CXorf53, Lys-63-specific deubiquitinase BRCC36, BRCA1-A complex subunit BRCC36, BRISC complex subunit BRCC36

Pathways: Positive Regulation of Response to DNA Damage Stimulus