Angiotensin 1-7 antibody

Catalog No. ABIN1860978

Product Details anti-Angiotensin 1-7 Antibody

Target: Angiotensin 1-7

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Angiotensin 1-7 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: It has been selected for its ability to recognize Ang1-7 in immunohistochemical staining and Western blotting.

Purification: Affinity Chromatography

Immunogen: Artificially Synthesized polypeptide, Ang1-7 conjugated to OVAAsp-Arg-Val-Tyr-Ile-His-Pro
The antibody is a rabbit polyclonal antibody raised against Ang1-7.

Isotype: IgG

Application Details

Application Notes: Western blotting: 1:100-400
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
Optimal working dilutions must be determined by end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Supplied as solution form in PBS, pH7.4, containing 0.02 % NaN3, 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid repeated freeze/thaw cycles

Storage: 4 °C

Storage Comment: Store at 2-8 °C for one month. Aliquot and store at -80 °C for 12 months.

Expiry Date: 12 months

References for anti-Angiotensin 1-7 antibody (ABIN1860978)

Wang, He, Guo, Zhang, Li, Han, Shen: "The ACE2-Ang (1-7)-Mas receptor axis attenuates cardiac remodeling and fibrosis in post-myocardial infarction." in: Molecular medicine reports, Vol. 16, Issue 2, pp. 1973-1981, (2018) (PubMed).

Target Details for Angiotensin 1-7

Target: Angiotensin 1-7

Abstract: Angiotensin 1-7 Products

Synonyms: ANHU antibody, SERPINA8 antibody, angiotensinogen antibody, AGT antibody