Stathmin 1 antibody (C-Term)

Catalog No. ABIN185573

Product Details anti-Stathmin 1 Antibody

Target: Stathmin 1 (STMN1)

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Goat

Clonality: Polyclonal

Conjugate: This Stathmin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Enzyme Immunoassay (EIA)

Purpose: STMN1 / Stathmin 1

Sequence: KNKESKDPAD ETEAD

Specificity: This antibody is expected to cross-react with isoform 1 a (NP_005554.1, NP_981944.1, NP_981946.1) only. The three reported isoforms (NP_005554.1, NP_981944.1 and NP_981946.1) represent identical protein.

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Grade: Verified

Immunogen: Peptide with sequence C-KNKESKDPADETEAD, from the C Terminus of the protein sequence according to NP_005554.1, NP_981944.1, NP_981946.1.

Isotype: IgG

Application Details

Application Notes:

Immunohistochemistry: Paraffin embedded Human Thymus and Tonsil. Recommended concentration: 3.75 μg/mL.

Western Blot: Approx 17 kDa band observed in Human Testis and Mouse Brain lysates (calculated MW of 17.3 kDa according to NP_005554.1, NP_981944.1 and NP_981946.1). Recommended concentration: 1-3 μg/mL.

Peptide ELISA: antibody detection limit dilution 1:1000.

Comment:

ELISA: This antibody has been successfully used in ELISA as described in the following paper: Song et al, Aging Cell. 2010 Aug,9(4):607-15, PMID: 20560902.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

References for anti-Stathmin 1 antibody (ABIN185573)

Watabe-Rudolph, Song, Lausser, Schnack, Begus-Nahrmann, Scheithauer, Rettinger, Otto, Tumani, Thal, Attems, Jellinger, Kestler, von Arnim, Rudolph: "Chitinase enzyme activity in CSF is a powerful biomarker of Alzheimer disease." in: Neurology, Vol. 78, Issue 8, pp. 569-77, (2012) (PubMed).

Song, von Figura, Liu, Kraus, Torrice, Dillon, Rudolph-Watabe, Ju, Kestler, Sanoff, Lenhard Rudolph: "Lifestyle impacts on the aging-associated expression of biomarkers of DNA damage and telomere dysfunction in human blood." in: Aging cell, Vol. 9, Issue 4, pp. 607-15, (2010) (PubMed).

Target Details for Stathmin 1

Target: Stathmin 1 (STMN1)

Alternative Name: STMN1 (STMN1 Products)

Synonyms: C1orf215 antibody, LAP18 antibody, Lag antibody, OP18 antibody, PP17 antibody, PP19 antibody, PR22 antibody, SMN antibody, 19k antibody, Lap18 antibody, Op18 antibody, P18 antibody, P19 antibody, Pig antibody, Pp17 antibody, Pp18 antibody, Pp19 antibody, Pr22 antibody, Smn antibody, prosolin antibody, op18 antibody, stathmin antibody, stmn1 antibody, stmn1a antibody, lag antibody, lap18 antibody, pp17 antibody, pp19 antibody, pr22 antibody, smn antibody, fj43c10 antibody, wu:fj38b07 antibody, wu:fj43c10 antibody, zgc:110159 antibody, cb959 antibody, wu:fb14e04 antibody, zgc:136942 antibody, stmn1-a antibody, stmn1b antibody, xo35 antibody, stathmin 1 antibody, stathmin 1 S homeolog antibody, stathmin 1b antibody, stathmin 1a antibody, stathmin-like antibody, stathmin antibody, stathmin 1 L homeolog antibody, STMN1 antibody, Stmn1 antibody, stmn1.S antibody, stmn1 antibody, stmn1b antibody, stmn1a antibody, LOC100229194 antibody, stmn1.L antibody

Background: STMN1, stathmin 1/oncoprotein 18 , LAP18, Lag, OP18, PP17, PP19, PR22, SMN , Pr22 protein, leukemia-associated phosphoprotein p18, metablastin, oncoprotein 18, phosphoprotein 19, prosolin, stathmin 1, stathmin 1 variant

Gene ID: 3925

NCBI Accession: NP_005554, NP_981944, NP_981946

Pathways: MAPK Signaling, Microtubule Dynamics