IL-6 Receptor antibody (Internal Region)
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- Target See all IL-6 Receptor (IL6R) Antibodies
- IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))
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Binding Specificity
- Internal Region
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Reactivity
- Human
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Host
- Goat
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Clonality
- Polyclonal
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Conjugate
- This IL-6 Receptor antibody is un-conjugated
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Application
- ELISA
- Purpose
- IL6R / CD126 (isoform 1)
- Sequence
- DNTSSHNRPD ARD
- Specificity
- This antibody is expected to recognise isoform 1 only (NP_000556.1)
- Predicted Reactivity
- Human
- Purification
- Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
- Grade
- Recent
- Immunogen
- Peptide with sequence C-DNTSSHNRPDARD, from the internal region of the protein sequence according to NP_000556.1.
- Isotype
- IgG
- Top Product
- Discover our top product IL6R Primary Antibody
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- Application Notes
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DS WB Results: Preliminary experiments gave an approx 26-28 kDa band in Human Bone Marrow and Tonsil lysates after 1 μg/mL antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 51.5 kDa according to NP_000556.1. The 26-28 kDa band was successfully blocked by incubation with the immunizing peptide. Have any further splice variants/modified forms been reported?
Peptide ELISA: antibody detection limit dilution 1:8000.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Minimize freezing and thawing.
- Storage
- -20 °C
- Storage Comment
- Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.
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- Target
- IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))
- Alternative Name
- IL6R / CD126 (IL6R Products)
- Synonyms
- IL6R antibody, il-6ra antibody, CD126 antibody, IL-6R-1 antibody, IL-6RA antibody, IL6Q antibody, IL6RA antibody, IL6RQ antibody, gp80 antibody, IL6R1 antibody, Il6ra antibody, IL-6Ralpha antibody, IL-6R antibody, Il6r antibody, interleukin 6 receptor antibody, interleukin 6 receptor, alpha antibody, IL6R antibody, il6r antibody, Il6r antibody, Il6ra antibody
- Background
- IL6R, interleukin 6 receptor , HGNC:6019, CD126, IL-6R-1, IL-6R-alpha, IL6RA, MGC104991 , CD126 antigen, interleukin 6 receptor alpha subunit
- Gene ID
- 3570
- NCBI Accession
- NP_000556
- Pathways
- JAK-STAT Signaling, Autophagy, Growth Factor Binding, Cancer Immune Checkpoints
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