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IFT74 antibody (C-Term)

Verified IFT74 Reactivity: Human ELISA, WB Host: Goat Polyclonal unconjugated
Catalog No. ABIN185213
  • Target See all IFT74 Antibodies
    IFT74 (Intraflagellar Transport Protein 74 Homolog (IFT74))
    Binding Specificity
    • 15
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 39
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 35
    • 2
    • 2
    Goat
    Clonality
    • 38
    • 1
    Polyclonal
    Conjugate
    • 15
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IFT74 antibody is un-conjugated
    Application
    • 13
    • 13
    • 12
    • 11
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    ELISA, Western Blotting (WB)
    Purpose
    CMG1 / CCDC2 / IFT74
    Sequence
    KTIVDALHST SGN
    Cross-Reactivity
    Human, Rat
    Purification
    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
    Grade
    Verified
    Immunogen
    Peptide with sequence C-KTIVDALHSTSGN, from the C Terminus of the protein sequence according to NP_001092692.1, NP_001092693.1, NP_079379.2, AAK77221.1.
    Isotype
    IgG
  • Application Notes

    Western Blot: Approx 70 kDa band observed in lysates of cell line HEK293 (calculated MW of 69.2 kDa according to AAK77221.1). The observed molecular weight corresponds to earlier findings in literature (Momeni et al, BMC Neurol. 2006 Dec 13,6:44., PMID: 17

    Peptide ELISA: antibody detection limit dilution 1:32000.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Minimize freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.
  • Boldt, Mans, Won, van Reeuwijk, Vogt, Kinkl, Letteboer, Hicks, Hurd, Naggert, Texier, den Hollander, Koenekoop, Bennett, Cremers, Gloeckner, Nishina, Roepman, Ueffing: "Disruption of intraflagellar protein transport in photoreceptor cilia causes Leber congenital amaurosis in humans and mice." in: The Journal of clinical investigation, Vol. 121, Issue 6, pp. 2169-80, (2011) (PubMed).

    Momeni, Schymick, Jain, Cookson, Cairns, Greggio, Greenway, Berger, Pickering-Brown, Chiò, Fung, Holtzman, Huey, Wassermann, Adamson, Hutton, Rogaeva, St George-Hyslop, Rothstein, Hardiman, Grafman et al.: "Analysis of IFT74 as a candidate gene for chromosome 9p-linked ALS-FTD. ..." in: BMC neurology, Vol. 6, pp. 44, (2007) (PubMed).

  • Target
    IFT74 (Intraflagellar Transport Protein 74 Homolog (IFT74))
    Alternative Name
    IFT74 (IFT74 Products)
    Synonyms
    CCDC2 antibody, DKFZp469F1522 antibody, 1700029H06Rik antibody, Ccdc2 antibody, Cmg1 antibody, b2b796Clo antibody, CMG-1 antibody, CMG1 antibody, intraflagellar transport protein 74/72 antibody, intraflagellar transport 74 antibody, intraflagellar transport protein 74 homolog antibody, IFT74 antibody, ift74 antibody, LOC100632007 antibody, LOC100649180 antibody, Ift74 antibody
    Background
    IFT74, CCDC2, CMG-1, FLJ22621, MGC111562, intraflagellar transport 74 homolog (Chlamydomonas), capillary morphogenesis protein 1, coiled-coil domain containing 2, CMG1
    Gene ID
    80173, 313365
    NCBI Accession
    NP_001092692, NP_001092693, NP_079379
    Pathways
    Hedgehog Signaling, Chromatin Binding
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