COPS2 antibody (C-Term)

Catalog No. ABIN184997

Product Details anti-COPS2 Antibody

Target: COPS2 (COP9 Constitutive Photomorphogenic Homolog Subunit 2 (Arabidopsis) (COPS2))

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Goat

Clonality: Polyclonal

Conjugate: This COPS2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Purpose: CSN2 / TRIP15

Sequence: LNSLNQAVVS KLA

Cross-Reactivity: Cow, Dog, Human, Mouse, Rat

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Grade: Verified

Immunogen: Peptide with sequence C-LNSLNQAVVSKLA, from the C Terminus of the protein sequence according to NP_004227.1, NP_001137359.1.

Isotype: IgG

Application Details

Application Notes:

Immunohistochemistry: In paraffin embedded Human Thyroid Gland shows nuclear and cytoplasm staining in activated epithelial cells Recommended concentration: 3-5 μg/mL.

Western Blot: Approx. 48 kDa band observed in lysates of Mouse putuitary cell line NIH3T3 (calculated MW of 51.6 kDa according to NP_004227.1). Recommended concentration: 1-3 μg/mL.

Peptide ELISA: antibody detection limit dilution 1:16000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

References for anti-COPS2 antibody (ABIN184997)

Besse, Campos, Webster, Darnay: "TRAF-interacting protein (TRIP) is a RING-dependent ubiquitin ligase." in: Biochemical and biophysical research communications, Vol. 359, Issue 3, pp. 660-4, (2007) (PubMed).

Target Details for COPS2

Target: COPS2 (COP9 Constitutive Photomorphogenic Homolog Subunit 2 (Arabidopsis) (COPS2))

Alternative Name: COPS2 (COPS2 Products)

Background: COPS2, TRIP15, COPS2, CSN2, thyroid receptor interacting protein 15, SGN2, COP9 constitutive photomorphogenic homolog subunit 2, thyroid receptor interacting protein 15, COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis), COP9, subunit 2,

Gene ID: 9318, 12848, 261736

NCBI Accession: NP_004227, NP_001137359

Pathways: Cell Division Cycle