Paired Box 3 antibody (AA 142-203)

Catalog No. ABIN1846350

Product Details anti-Paired Box 3 Antibody

Target: Paired Box 3 (PAX3)

Binding Specificity: AA 142-203

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Paired Box 3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human PAX3 (AA: 142-203) expressed in E. coli.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.

Target Details for Paired Box 3

Target: Paired Box 3 (PAX3)

Alternative Name: PAX3 (PAX3 Products)

Background: This gene is a member of the paired box (PAX) family of transcription factors.Members of the PAX family typically contain a paired box domain and a paired-type homeodomain.These genes play critical roles during fetal development.Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma.The translocation t (2,13) (q35,q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma.Alternative splicing results in transcripts encoding isoforms with different C-termini.

Molecular Weight: 53 kDa

Gene ID: 5077

Pathways: Sensory Perception of Sound, Tube Formation