Cadherin 5 antibody (AA 29-223)

Catalog No. ABIN1846316

Product Details anti-Cadherin 5 Antibody

Target: Cadherin 5 (CDH5)

Binding Specificity: AA 29-223

Reactivity: Human, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This Cadherin 5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CDH5 (AA: 29-223) expressed in E. coli.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.

Target Details for Cadherin 5

Target: Cadherin 5 (CDH5)

Alternative Name: CDH5 (CDH5 Products)

Background: This gene is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer.The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail.Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions.An alternative splice variant has been described but its full length sequence has not been determined.

Molecular Weight: 87.5 kDa

Gene ID: 1003, 307618

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2