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CAPZB antibody (C-Term)

Verified CAPZB Reactivity: Human, Mouse, Rat, Pig WB, ELISA Host: Goat Polyclonal unconjugated
Catalog No. ABIN184616
  • Target See all CAPZB Antibodies
    CAPZB (Capping Protein (Actin Filament) Muscle Z-Line, beta (CAPZB))
    Binding Specificity
    • 8
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 28
    • 8
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Pig
    Host
    • 25
    • 3
    Goat
    Clonality
    • 26
    • 2
    Polyclonal
    Conjugate
    • 23
    • 1
    • 1
    • 1
    • 1
    • 1
    This CAPZB antibody is un-conjugated
    Application
    • 27
    • 13
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    Purpose
    CAPZB
    Sequence
    NDLVEALKRK QQC
    Specificity
    This antibody is expected to be specific for the beta2 isoform of capping protein, found in non-muscle cells and should not recognise the beta1 form.
    Cross-Reactivity
    Cow, Dog, Human, Mouse, Pig, Rat
    Purification
    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
    Grade
    Verified
    Immunogen
    Peptide with sequence NDLVEALKRKQQC, from the C Terminus of the protein sequence according to NP_004921.1.
    Isotype
    IgG
  • Application Notes

    Western Blot: Approx 30 kDa band observed in lysates of cell lines Jurkat, HeLa and NIH-3T3 and approx 28 kDa band observed in Mouse, Rat and Pig Heart lysates (calculated MW of 30.6 kDa according to Human NP_004921.1 and 31.3 kDa according to Mouse NP_00103

    Peptide ELISA: antibody detection limit dilution 1:32000.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Minimize freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.
  • Wang, Chen, Wu, Tsai, Shyue, Yang, Tzeng: "Reduction in antioxidant enzyme expression and sustained inflammation enhance tissue damage in the subacute phase of spinal cord contusive injury." in: Journal of biomedical science, Vol. 18, pp. 13, (2011) (PubMed).

  • Target
    CAPZB (Capping Protein (Actin Filament) Muscle Z-Line, beta (CAPZB))
    Alternative Name
    CAPZB (CAPZB Products)
    Background
    CAPZB, capping protein (actin filament) muscle Z-line, beta, CAPB, CAPZ, CAPPB, Cap Z, RP4-657E11.7, MGC104401, MGC129749, MGC129750, Cap Z, F-actin capping protein beta subunit
    Gene ID
    832, 12345
    NCBI Accession
    NP_004921
    Pathways
    Regulation of Actin Filament Polymerization
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