CD59 antibody (AA 31-111)
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- Target See all CD59 Antibodies
- CD59
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Binding Specificity
- AA 31-111
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD59 antibody is un-conjugated
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Application
- Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Immunofluorescence (fixed cells) (IF/ICC)
- Purification
- Purified antibody
- Immunogen
- Purified recombinant fragment of human CD59 (AA: 31-111) expressed in E. Coli.
- Isotype
- IgG1
- Top Product
- Discover our top product CD59 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.0 mg/mL
- Buffer
- PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
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- Target
- CD59
- Alternative Name
- CD59 (CD59 Products)
- Synonyms
- 16.3A5 antibody, 1F5 antibody, EJ16 antibody, EJ30 antibody, EL32 antibody, G344 antibody, HRF-20 antibody, HRF20 antibody, MAC-IP antibody, MACIF antibody, MEM43 antibody, MIC11 antibody, MIN1 antibody, MIN2 antibody, MIN3 antibody, MIRL antibody, MSK21 antibody, p18-20 antibody, Cd59a antibody, Cd59b antibody, MACIP antibody, CD59 molecule (CD59 blood group) antibody, CD59 molecule antibody, CD59 antibody, Cd59 antibody
- Background
- This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation.
- Molecular Weight
- 14.2 kDa
- Gene ID
- 966
- UniProt
- P13987
- Pathways
- Complement System
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