OLIG2 antibody

Catalog No. ABIN1845900

Product Details anti-OLIG2 Antibody

Target: OLIG2 (Oligodendrocyte Lineage Transcription Factor 2 (OLIG2))

Reactivity: Human, Mouse, Rat, Chicken

Host: Mouse

Clonality: Monoclonal

Conjugate: This OLIG2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (fixed cells) (IF/ICC)

Immunogen: Purified recombinant fragment of human OLIG2 expressed in E. coli.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.

Target Details for OLIG2

Target: OLIG2 (Oligodendrocyte Lineage Transcription Factor 2 (OLIG2))

Alternative Name: OLIG2 (OLIG2 Products)

Background: This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain.The protein is an essential regulator of ventral neuroectodermal progenitor cell fate.The gene is involved in a chromosomal translocation t (14,21) (q11.2,q22) associated with T-cell acute lymphoblastic leukemia.Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome.Tissue specificity: Expressed in the brain, in oligodendrocytes.Strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas.Expression in glioblastomas highly variable.

Molecular Weight: 32 kDa

Gene ID: 10215, 50913, 304103