Lp(a) antibody (AA 4330-4521)

Catalog No. ABIN1845714

Product Details anti-Lp(a) Antibody

Target: Lp(a) (Lipoprotein (Lp(a)))

Binding Specificity: AA 4330-4521

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Lp(a) antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (fixed cells) (IF/ICC)

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human LPA (AA: 4330-4521) expressed in E. coli.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.

Target Details for Lp(a)

Target: Lp(a) (Lipoprotein (Lp(a)))

Alternative Name: LPA

Background: The protein encoded by this gene is a serine proteinase that inhibits the activity of tissue-type plasminogen activator I.The encoded protein constitutes a substantial portion of lipoprotein (a) and is proteolytically cleaved, resulting in fragments that attach to atherosclerotic lesions and promote thrombogenesis.Elevated plasma levels of this protein are linked to atherosclerosis.Depending on the individual, the encoded protein contains 2-43 copies of kringle-type domains.The allele represented here contains 15 copies of the kringle-type repeats and corresponds to that found in the reference genome sequence.

Molecular Weight: 501 kDa

Gene ID: 4018

UniProt: P08519