FLIP antibody (AA 100-251)

Catalog No. ABIN1845710

Product Details anti-FLIP Antibody

Target: FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))

Binding Specificity: AA 100-251

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This FLIP antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CFLAR (AA: 100-251) expressed in E. coli.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.

Target Details for FLIP

Target: FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))

Alternative Name: CFLAR (CFLAR Products)

Background: The protein encoded by this gene is a regulator of apoptosis and is structurally similar to caspase-8.However, the encoded protein lacks caspase activity and appears to be itself cleaved into two peptides by caspase-8.Several transcript variants encoding different isoforms have been found for this gene, and partial evidence for several more variants exists.

Molecular Weight: 55 kDa

Gene ID: 8837

Pathways: Apoptosis, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development