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CD25 antibody (AA 34-139)
IL2RA
Reactivity: Human, Mouse, Rat, Monkey
WB, IHC, ELISA, IF/ICC
Host: Mouse
Monoclonal
unconjugated
Product Details anti-CD25 Antibody
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Target
See all CD25 (IL2RA) Antibodies
CD25 (IL2RA)
(Interleukin 2 Receptor, alpha (IL2RA))
Binding Specificity
All epitopes for CD25 antibodies
AA 34-139
Reactivity
All reactivities for CD25 antibodies
Human, Mouse, Rat, Monkey
Host
All hosts for CD25 antibodies
Mouse
Clonality
All clonalities for CD25 antibodies
Monoclonal
Conjugate
All conjugates for CD25 antibodies
This CD25 antibody is un-conjugated
Application
All applications for CD25 antibodies
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (fixed cells) (IF/ICC)
Purification
Purified antibody
Immunogen
Purified recombinant fragment of human IL2RA (AA: 34-139) expressed in E. coli.
Isotype
IgG1
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1.0 mg/mL
Buffer
PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Target Details for CD25
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Target
CD25 (IL2RA)
(Interleukin 2 Receptor, alpha (IL2RA))
Alternative Name
IL2RA (IL2RA Products )
Synonyms
CD25 antibody, IDDM10 antibody, IL2R antibody, TCGFR antibody, IL2RAC antibody, IL-2RA antibody, Il2r antibody, Ly-43 antibody, interleukin 2 receptor subunit alpha antibody, interleukin-2 receptor subunit alpha-like antibody, interleukin 2 receptor, alpha chain antibody, IL2RA antibody, Il2ra antibody, LOC100222957 antibody
Background
The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor.Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor.Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis.Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown.Mutations in this gene are associated with interleukin 2 receptor alpha deficiency., , , ,.
Molecular Weight
30.8 kDa
Gene ID
3559, 16184, 574300
Pathways
JAK-STAT Signaling , Growth Factor Binding , Activated T Cell Proliferation
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