Tropomodulin 1 antibody (N-Term)

Catalog No. ABIN1820111

Product Details anti-Tropomodulin 1 Antibody

Target: Tropomodulin 1 (TMOD1)

Binding Specificity: AA 6-57, N-Term

Reactivity: Chicken, Avian, Mammalian

Host: Mouse

Clonality: Monoclonal

Conjugate: This Tropomodulin 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Functional Studies (Func)

Specificity: Recognizes an epitope between amino acid residues 6-57 within the N-terminal (NT) region of Tropomodulin 1 (Tmod1), otherwise known as erythrocyte tropomodulin (E-Tmod). Tmod1 is a sarcomeric protein highly expressed by erythrocytes, heart and skeletal muscle, which binds to and caps pointed ends of actin filaments to prevent thin filament elongation. The binding of the N-terminal region of Tmod1 with the actin-binding protein tropomyosin blocks the elongation and depolymerization of actin filaments, contributing to the geometry of the membrane skeleton. Clone TRM-17 functionally inhibits the binding of Tmod1 to tropomyosin.

Purification: Protein A purified

Immunogen: Recombinant chicken E-Tmod.

Type of Immunogen: Recombinant protein

Clone: TRM-17 (Mab17)

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Target Species of Antibody: Chicken

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: 4°C or -20°C, Avoid freeze-thaw cycles.

Target Details for Tropomodulin 1

Target: Tropomodulin 1 (TMOD1)

Alternative Name: TMOD1 / Tropomodulin 1 (TMOD1 Products)

Synonyms: tropomodulin-1 antibody, TMOD1 antibody, si:ch211-288h2.6 antibody, D9S57E antibody, ETMOD antibody, TMOD antibody, E-Tmod antibody, Tmod antibody, tropomodulin 1 antibody, TMOD1 antibody, tmod1 antibody, Tmod1 antibody

Background: Name/Gene ID: TMOD1

Synonyms: TMOD1, D9S57E, E-Tmod, E-tropomodulin, Erythrocyte tropomodulin, ETMOD, TMOD, Tropomodulin-1, Tropomodulin 1

Gene ID: 7111