Ubiquitin antibody

Catalog No. ABIN1819292

Product Details anti-Ubiquitin Antibody

Target: Ubiquitin

Reactivity: Cow

Host: Sheep

Clonality: Polyclonal

Conjugate: This Ubiquitin antibody is un-conjugated

Application: ELISA

Specificity: Recognizes ubiquitin, a 8.6kD cytoplasmic and nuclear protein which is highly conserved across species. Ubiquitin functions as a protein modifier which covalently attaches to lysines as either a monomer or as a lysine-linked polymer. Attachment as a Lys-48 polymer usually leads to the target protein undergoing proteolytic degradation. Attachment as a monomer does not result in degradation and may be linked to functions including maintenance of chromatin structure, regulation of gene expression, stress response and DNA repair. Ubiquitin can be detected in both normal and diseased brain tissues including the neurofibrillary tangles of Alzheimer's disease, Lewy bodies in Parkinson's disease and Pick bodies in Picka€™s disease.

Purification: Protein G purified

Immunogen: Native ubiquitin from bovine erythrocytes.

Type of Immunogen: Native protein

Isotype: IgG

Application Details

Application Notes: Approved: ELISA (1:100 - 1:2000)

Comment:

Target Species of Antibody: Bovine

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: 4°C or -20°C, Avoid freeze-thaw cycles.

Target Details for Ubiquitin

Target: Ubiquitin

Alternative Name: Ubiquitin (Ubiquitin Products)

Pathways: Mitotic G1-G1/S Phases, Ubiquitin Proteasome Pathway