Siglec E antibody

Catalog No. ABIN1818480

Product Details anti-Siglec E Antibody

Target: Siglec E (Siglece) (Sialic Acid Binding Ig-Like Lectin E (Siglece))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This Siglec E antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP)

Specificity: Mouse Siglece

Purification: Protein G purified

Immunogen: Mouse CD170 transfected L cells.

Type of Immunogen: Cells

Clone: 8D2

Isotype: IgG2b

Application Details

Application Notes: Approved: Flo (5 - 10 μg/mL), IP

Usage: IP: 2 μg/300 μL of cell extract from 5x10⁶ cells,

Comment:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.2, 50 % glycerol

Storage: -20 °C

Storage Comment: Store at -20°C.

References for anti-Siglec E antibody (ABIN1818480)

Smith, Deutzmann, Correa, Delaveris, Dhanasekaran, Dove, Sullivan, Wisnovsky, Stark, Pluvinage, Swaminathan, Riley, Rajan, Majeti, Felsher, Bertozzi: "MYC-driven synthesis of Siglec ligands is a glycoimmune checkpoint." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 120, Issue 11, pp. e2215376120, (2023) (PubMed).

Target Details for Siglec E

Target: Siglec E (Siglece) (Sialic Acid Binding Ig-Like Lectin E (Siglece))

Alternative Name: Siglece (Siglece Products)

Synonyms: Cd170 antibody, Siglec12 antibody, Siglec5 antibody, Siglec9 antibody, Siglecl1 antibody, mSiglec-E antibody, sialic acid binding Ig-like lectin E antibody, Siglece antibody

Background: Name/Gene ID: Siglece

Synonyms: Siglece, CD170, MSiglec-E

Gene ID: 83382