FeLV Envelope Glycoprotein antibody
Reactivity: Feline Leukemia Virus (FeLV)
IHC (p), IP, WB
Host: Mouse
Monoclonal
PF6J-2A1
unconjugated
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- Target
- FeLV Envelope Glycoprotein
- Reactivity
- Feline Leukemia Virus (FeLV)
-
Host
- Mouse
-
Clonality
- Monoclonal
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Conjugate
- Un-conjugated
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Application
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
- Characteristics
- Synonyms: Feline leukemia virus env, gp70, p15E
- Purification
- Affinity chromatography on Protein A
- Clone
- PF6J-2A1
- Isotype
- IgG2a
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-
- Application Notes
-
Immunohistochemistry on paraffin sections. Immunoprecipitation. Western Blot: 1: 2,000, detects band/s of approximately 15 kDa and 25 kDa under reducingconditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0mg/mL
- Buffer
- PBS, pH 7.2 containing 0.05 % Sodium Azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
-
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. - Expiry Date
- 12 months
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- Target
- FeLV Envelope Glycoprotein
- Target Type
- Viral Protein
- Background
- Persistent infection of cats with the oncoretrovirus FeLV can result in the non-neoplastic condition known as FeLV-associated enteritis (FAE). Studies have shown strong expression of the major FeLV proteins p15e and gp70 in intestinal crypt epithelial cells of cats with FAE, compared to FeLV-positive cats without intestinal alterations, thereby suggesting a pathogenic role for these envelope proteins/precursors in FAE.Synonyms: Feline leukemia virus env, gp70, p15E
- UniProt
- P06752
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