Tenascin R antibody

Catalog No. ABIN1742431

Product Details anti-Tenascin R Antibody

Target: Tenascin R (TNR) (Tenascin R (Restrictin, Janusin) (TNR))

Reactivity: Rat, Mouse, Chicken, Cow

Host: Mouse

Clonality: Monoclonal

Conjugate: This Tenascin R antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), Immunocytochemistry (ICC)

Specificity: Specific for Tenascin-R.

Purification: purified IgG

Clone: 619

Isotype: IgG1

Application Details

Application Notes: WB: 1 : 1000 (AP staining)
IP: not tested yet
ICC: 1 : 500

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: For reconstitution add 100 µL H2O to get a 1mg/ml solution of antibody in PBS. Then aliquot and store at -20 °C until use.

Buffer: PBS

Handling Advice: Do not store diluted antibody solutions unless you add detergent or carrier proteins such as goat serum, BSA or others. IgG sticks to glass and plastic. Any IgG solution below 0.1 mg/mL protein will quickly adsorb and denature and thus loose activity! Repetitive freeze-thawing of dilute purified IgG is almost certain to lead to substantial losses.

Storage: -20 °C

Storage Comment: Unlabeled antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4 °C for several years.

References for anti-Tenascin R antibody (ABIN1742431)

Arranz, Perkins, Irie, Lewis, Hrabe, Xiao, Itano, Kimata, Hrabetova, Yamaguchi: "Hyaluronan deficiency due to Has3 knock-out causes altered neuronal activity and seizures via reduction in brain extracellular space." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 34, Issue 18, pp. 6164-76, (2014) (PubMed).

Apostolova, Irintchev, Schachner: "Tenascin-R restricts posttraumatic remodeling of motoneuron innervation and functional recovery after spinal cord injury in adult mice." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 26, Issue 30, pp. 7849-59, (2006) (PubMed).

Schuster, Krug, Stalder, Hackel, Gerardy-Schahn, Schachner et al.: "Immunoelectron microscopic localization of the neural recognition molecules L1, NCAM, and its isoform NCAM180, the NCAM-associated polysialic acid, beta1 integrin and the extracellular matrix ..." in: Journal of neurobiology, Vol. 49, Issue 2, pp. 142-58, (2001) (PubMed).

Weber, Bartsch, Rasband, Czaniera, Lang, Bluethmann, Margolis, Levinson, Shrager, Montag, Schachner: "Mice deficient for tenascin-R display alterations of the extracellular matrix and decreased axonal conduction velocities in the CNS." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 19, Issue 11, pp. 4245-62, (1999) (PubMed).

Target Details for Tenascin R

Target: Tenascin R (TNR) (Tenascin R (Restrictin, Janusin) (TNR))

Alternative Name: Tenascin-R (TNR Products)

Synonyms: TN-R antibody, J1-tenascin antibody, janusin antibody, restrictin antibody, J1NRM antibody, tenascin R antibody, TNR antibody, Tnr antibody

Background: Synonyms: TNR, J1-160/180

Pathways: Regulation of Cell Size