NEFL antibody (AA 1-284)

Catalog No. ABIN1742358

Product Details anti-NEFL Antibody

Target: NEFL (Neurofilament, Light Polypeptide (NEFL))

Binding Specificity: AA 1-284

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NEFL antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Specificity: Specific for neurofilament L.

Purification: antiserum

Immunogen: Recombinant Strep-Tag® fusion protein of human neurofilament L (aa 1-284).

Application Details

Application Notes: WB: 1 : 1000 (AP staining)
ICC: 1 : 500
IHC: 1 : 200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS

Handling Advice: Crude antisera are more robust than monoclonals. With anti-microbials added, they may be stored at 4 °C.
Serum does not contain active proteases, in fact, serum itself contains a powerful cocktail of protease inhibitors. Frozen storage (-20 °C),however, is preferable.

Storage: 4 °C/-20 °C

Storage Comment: Unlabeled antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4 °C for several years.

References for anti-NEFL antibody (ABIN1742358)

Richard, Kurdakova, Baches, Bayer, Weggen, Wirths: "Gene Dosage Dependent Aggravation of the Neurological Phenotype in the 5XFAD Mouse Model of Alzheimer's Disease." in: Journal of Alzheimer's disease : JAD, Vol. 45, Issue 4, pp. 1223-36, (2015) (PubMed).

Pérez-García, Burden: "Increasing MuSK activity delays denervation and improves motor function in ALS mice." in: Cell reports, Vol. 2, Issue 3, pp. 497-502, (2012) (PubMed).

Wenker, Chamorro, Vota, Callero, Vittori, Nesse: "Differential antiapoptotic effect of erythropoietin on undifferentiated and retinoic acid-differentiated SH-SY5Y cells." in: Journal of cellular biochemistry, Vol. 110, Issue 1, pp. 151-61, (2010) (PubMed).

Target Details for NEFL

Target: NEFL (Neurofilament, Light Polypeptide (NEFL))

Alternative Name: Neurofilament L (NEFL Products)

Synonyms: NEFL antibody, nefl antibody, zgc:136626 antibody, AI847934 antibody, CMT2E antibody, NF-L antibody, NF68 antibody, Nfl antibody, CMT1F antibody, NFL antibody, XNF-L antibody, neurofilament light antibody, neurofilament, light polypeptide antibody, neurofilament, light polypeptide b antibody, neurofilament, light L homeolog antibody, NEFL antibody, neflb antibody, Nefl antibody, nefl.L antibody

Background: Synonyms: NF-L, NF 68