SHANK1 antibody (AA 135-149)

Catalog No. ABIN1742345

Product Details anti-SHANK1 Antibody

Target: SHANK1 (SH3 and Multiple Ankyrin Repeat Domains 1 (SHANK1))

Binding Specificity: AA 135-149

Reactivity: Human, Rat, Mouse, Dog, Monkey, Pig, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SHANK1 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: Specific for shank 1.

Purification: antiserum

Immunogen: Synthetic peptide ERLLREYPQSFEKGV (aa 135-149) coupled to key-hole limpet hemocyanin via an added C-terminal cysteine residue.

Application Details

Application Notes: WB: 1 : 1000 (AP staining)
IP: not tested yet
ICC: not tested yet
IHC: not tested yet

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS

Handling Advice: Crude antisera are more robust than monoclonals. With anti-microbials added, they may be stored at 4 °C.
Serum does not contain active proteases, in fact, serum itself contains a powerful cocktail of protease inhibitors. Frozen storage (-20 °C),however, is preferable.

Storage: 4 °C/-20 °C

Storage Comment: Unlabeled antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4 °C for several years.

References for anti-SHANK1 antibody (ABIN1742345)

Williams, DeSpenza, Li, Gulledge, Luikart: "Hyperactivity of newborn Pten knock-out neurons results from increased excitatory synaptic drive." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 3, pp. 943-59, (2015) (PubMed).

Target Details for SHANK1

Target: SHANK1 (SH3 and Multiple Ankyrin Repeat Domains 1 (SHANK1))

Alternative Name: Shank 1 (SHANK1 Products)

Synonyms: SPANK-1 antibody, SSTRIP antibody, synamon antibody, Shank1a antibody, Spank1 antibody, Sstrip antibody, SH3 and multiple ankyrin repeat domains 1 antibody, SHANK1 antibody, Shank1 antibody

Pathways: Synaptic Membrane, Maintenance of Protein Location