UNC13A/Munc13-1 antibody (AA 3-317)

Catalog No. ABIN1742277

This anti-UNC13A/Munc13-1 antibody is a Rabbit Polyclonal antibody detecting UNC13A/Munc13-1 in WB, IP, ICC and IHC. Suitable for Human, Mouse, Rat and Zebrafish (Danio rerio). This Primary Antibody has been cited in 3+ publications.

Quick Overview for UNC13A/Munc13-1 antibody (AA 3-317) (ABIN1742277)

Target: UNC13A/Munc13-1 (UNC13A) (Unc-13 Homolog A (UNC13A))

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UNC13A/Munc13-1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (IHC)

Product Details anti-UNC13A/Munc13-1 Antibody

Binding Specificity: AA 3-317

Specificity: Specific for munc 13-1.

Immunogen: Recombinant rat munc 13-1 (aa 3-317).

Application Details

Application Notes: WB: 1:1000, ICC: 1:500, IHC: 1:200,

Comment:

IP: For most effective IP use the solubilization protocol described in the ELISA protocol. Consider that protein-protein interaction may be affected. ICC: This antibody gives much better results in ICC than the monoclonal antibody. ELISA: Suitable as detector antibody for sandwich-ELISA with ABIN1742276 as capture antibody (protocol for sandwich-ELISA).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: For reconstitution add 200µl H2O.

Preservative: Azide and BSA free

Handling Advice: Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

Storage: 4 °C/-20 °C

Storage Comment: Reconstitute and aliquot and store at -20°C until use. Antibodies should be stored at +4°C when still lyophilized.

References for anti-UNC13A/Munc13-1 antibody (ABIN1742277)

Fernandes, Riordan, Nomura, Remmers, Kraniotis, Marshall, Kukreja, Vassar, Contractor: "Epac2 Mediates cAMP-Dependent Potentiation of Neurotransmission in the Hippocampus." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 16, pp. 6544-53, (2015) (PubMed).

Juranek, Mukherjee, Siddiqui, Kaplan, Li, Ahnert-Hilger, Jahn, Calka: "Active zone protein expression changes at the key stages of cerebellar cortex neurogenesis in the rat." in: Acta histochemica, Vol. 115, Issue 6, pp. 616-25, (2013) (PubMed).

Rinetti, Schweizer: "Ubiquitination acutely regulates presynaptic neurotransmitter release in mammalian neurons." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 9, pp. 3157-66, (2010) (PubMed).

Target Details for UNC13A/Munc13-1

Target: UNC13A/Munc13-1 (UNC13A) (Unc-13 Homolog A (UNC13A))

Alternative Name: Munc 13-1

Pathways: Skeletal Muscle Fiber Development, Synaptic Vesicle Exocytosis