GRIN1/NMDAR1 antibody (AA 35-53)

Catalog No. ABIN1742246

The Rabbit Polyclonal anti-GRIN1/NMDAR1 antibody has been validated for WB, ELISA and IP. It is suitable to detect GRIN1/NMDAR1 in samples from Human, Rat and Mouse. There are 2+ publications available.

Quick Overview for GRIN1/NMDAR1 antibody (AA 35-53) (ABIN1742246)

Target: GRIN1/NMDAR1 (GRIN1) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRIN1/NMDAR1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Product Details anti-GRIN1/NMDAR1 Antibody

Binding Specificity: AA 35-53

Specificity: Specific for GluN 1.

Purification: Affinity purified with the immunogen.

Immunogen: Synthetic peptide (aa 35-53 of rat GluN 1) coupled to key-hole limpet hemocyanin via an added N-terminal cysteine residue.

Application Details

Application Notes: WB: 1:1000, ICC: not recommended IHC: not recommended

Comment:

IP: For most effective IP use the solubilization protocol described in the ELISA protocol. Consider that protein-protein interaction may be affected. IHC: Antibody 2, ABIN1742247, is recommended for IHC. ELISA: Suitable as detector antibody for sandwich-ELISA as capture antibody (protocol for sandwich-ELISA).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: For reconstitution add 50µl H2O to get a 1mg/ml solution in PBS.

Buffer: PBS. Albumin was added for stabilization.

Preservative: Azide and BSA free

Handling Advice: Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

Storage: -20 °C

Storage Comment: Reconstitute and aliquot and store at -20°C to -80°C until use. Antibodies should be stored at +4°C when still lyophilized.

References for anti-GRIN1/NMDAR1 antibody (ABIN1742246)

Vasileva, Horstmann, Geumann, Gitler, Kuner: "Synapsin-dependent reserve pool of synaptic vesicles supports replenishment of the readily releasable pool under intense synaptic transmission." in: The European journal of neuroscience, Vol. 36, Issue 8, pp. 3005-20, (2012) (PubMed).

Ribic, Flügge, Schlumbohm, Mätz-Rensing, Walter, Fuchs: "Activity-dependent regulation of MHC class I expression in the developing primary visual cortex of the common marmoset monkey." in: Behavioral and brain functions : BBF, Vol. 7, pp. 1, (2011) (PubMed).

Target Details for GRIN1/NMDAR1

Target: GRIN1/NMDAR1 (GRIN1) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1))

Alternative Name: NMDA-Receptor 1

Pathways: Synaptic Membrane, Feeding Behaviour, Regulation of long-term Neuronal Synaptic Plasticity