Syntaxin 11 antibody (AA 1-15)

Catalog No. ABIN1742227

Product Details anti-Syntaxin 11 Antibody

Target: Syntaxin 11 (STX11)

Binding Specificity: AA 1-15

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Syntaxin 11 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Specificity: Specific for syntaxin 11

Cross-Reactivity (Details): no cross reactivity to other syntaxins.

Purification: Affinity purified with the immunogen. Rabbit serum albumin was added for stabilization.

Immunogen: Synthetic peptide (aa 1-15 of mouse syntaxin 11) coupled to KLH via a C-terminal added cysteine.

Application Details

Application Notes: WB: 1 : 1000 (AP staining)
ICC: 1 : 100
IHC: not tested yet

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: For reconstitution add 50 µL H2O to get a 1mg/ml solution of antibody in PBS. Then aliquot and store at -20 °C until use.

Buffer: PBS

Handling Advice: Affinity purified antibodies are less robust than antisera, since protease inhibitors are also removed during purification. Hence, storage at 4 °C for prolonged periods (i.e. several weeks), is not recommended.

Storage: -20 °C

Storage Comment: Unlabeled lyophilized antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4°C for several years. Lyophilized antibodies must not be stored in the freezer, they may be destroyed!

References for anti-Syntaxin 11 antibody (ABIN1742227)

Koseoglu, Peters, Fitch-Tewfik, Aisiku, Danglot, Galli, Flaumenhaft: "VAMP-7 links granule exocytosis to actin reorganization during platelet activation." in: Blood, Vol. 126, Issue 5, pp. 651-60, (2015) (PubMed).

Golebiewska, Harper, Williams, Savage, Goggs, Fischer von Mollard, Poole: "Syntaxin 8 regulates platelet dense granule secretion, aggregation, and thrombus stability." in: The Journal of biological chemistry, Vol. 290, Issue 3, pp. 1536-45, (2015) (PubMed).

Ye, Karim, Al Hawas, Pessin, Filipovich, Whiteheart: "Syntaxin-11, but not syntaxin-2 or syntaxin-4, is required for platelet secretion." in: Blood, Vol. 120, Issue 12, pp. 2484-92, (2012) (PubMed).

Target Details for Syntaxin 11

Target: Syntaxin 11 (STX11)

Alternative Name: Syntaxin 11 (STX11 Products)

Synonyms: MGC79075 antibody, MGC89708 antibody, FHL4 antibody, HLH4 antibody, HPLH4 antibody, 5830405C08Rik antibody, syntaxin 11 antibody, syntaxin 11 S homeolog antibody, STX11 antibody, stx11.S antibody, stx11 antibody, Stx11 antibody