SYN2 antibody (AA 440-458)

Catalog No. ABIN1742208

Product Details anti-SYN2 Antibody

Target: SYN2 (Synapsin II (SYN2))

Binding Specificity: AA 440-458

Reactivity: Mouse, Human, Rat, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SYN2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Specificity: Specific for synapsins 2a and 2b

Cross-Reactivity (Details): no cross-reactivity to synapsin 1a/b.

Purification: Affinity purified with the immunogen. Rabbit serum albumin was added for stabilization.

Immunogen: Synthetic peptide (aa 440-458 of mouse synapsin 2) coupled to KLH via an N-terminal added cysteine.

Application Details

Application Notes: WB: 1 : 1000 (AP staining)
ICC: 1 : 500 up to 1 : 1000
IHC: 1 : 200

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: For reconstitution add 50 µL H2O to get a 1mg/ml solution of antibody in PBS. Then aliquot and store at -20 °C until use.

Buffer: PBS

Handling Advice: Affinity purified antibodies are less robust than antisera, since protease inhibitors are also removed during purification. Hence, storage at 4 °C for prolonged periods (i.e. several weeks), is not recommended.

Storage: -20 °C

Storage Comment: Unlabeled lyophilized antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4°C for several years. Lyophilized antibodies must not be stored in the freezer, they may be destroyed!

References for anti-SYN2 antibody (ABIN1742208)

Shulman, Stavsky, Fedorova, Mikulincer, Atias, Radinsky, Kahn, Slutsky, Gitler: "ATP binding to synaspsin IIa regulates usage and clustering of vesicles in terminals of hippocampal neurons." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 3, pp. 985-98, (2015) (PubMed).

Chen, Yu, Huang, Yu, Zhu, Lam, Lam, Zhou: "Prenatal transfer of polybrominated diphenyl ethers (PBDEs) results in developmental neurotoxicity in zebrafish larvae." in: Environmental science & technology, Vol. 46, Issue 17, pp. 9727-34, (2012) (PubMed).

Target Details for SYN2

Target: SYN2 (Synapsin II (SYN2))

Alternative Name: Synapsin 2 (SYN2 Products)

Synonyms: synII antibody, synIIa antibody, synIIb antibody, syn1 antibody, syn2 antibody, zgc:92311 antibody, MGC115109 antibody, SYN2 antibody, SYNII antibody, SYNIIa antibody, SYNIIb antibody, 2900074L19Rik antibody, AI836018 antibody, AI841723 antibody, synapsin II L homeolog antibody, synapsin II antibody, synapsin IIa antibody, synapsin II S homeolog antibody, synapsin-2 antibody, syn2.L antibody, SYN2 antibody, syn2a antibody, syn2.S antibody, EDI_190690 antibody, Syn2 antibody