pADPR antibody (Agarose Beads)
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- Target
- pADPR
- Reactivity
- All Species
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- Agarose Beads
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Application
- Immunoprecipitation (IP)
- Characteristics
- Recognizes DNA-damage and apoptosis related poly-ADP ribosylated proteins and poly (ADP-ribose) polymer
- Purification
- Protein A affinity column
- Immunogen
- poly(ADP-ribose)
- Clone
- 10H
- Isotype
- IgG3
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- Application Notes
- 0.5 µg/IP reaction
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS, pH 7.4 with 0,05 % sodium azides
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid freeze/thaw cycles.
- Storage
- 4 °C
- Storage Comment
- Stable for 1 year from date of shipment when stored at -20 °C or -70 °C. Stable for at least 1 month at 4 °C.
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Involvement of poly(ADP-Ribose) polymerase 1 and poly(ADP-Ribosyl)ation in regulation of centrosome function." in: Molecular and cellular biology, Vol. 23, Issue 7, pp. 2451-62, (2003) (PubMed).
: "
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Involvement of poly(ADP-Ribose) polymerase 1 and poly(ADP-Ribosyl)ation in regulation of centrosome function." in: Molecular and cellular biology, Vol. 23, Issue 7, pp. 2451-62, (2003) (PubMed).
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- Target
- pADPR
- Background
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Synonyms: poly(ADP-ribose)
Poly(ADP-ribose) or pADPr is a polymer synthesized by a class of enzymes named poly(ADP-ribose) polymerase (PARP). Using NAD+ as substrate, PARP catalyzes the formation of the polymer pADPr, with chain lengths ranging from 2 to 300 residues, containing approximately 2 % branching in the chain. pADPr becomes attached to nuclear proteins, and to PARP itself (automodification).
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