UBC antibody (N-Term)

Catalog No. ABIN4889895

Product Details anti-UBC Antibody

Target: UBC (Ubiquitin C (UBC))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBC antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: Reacts with the N-terminus part of human UBC / Ubiquitin C

Purification: Purified (protein G)

Immunogen: KLH conjugated synthetic peptide selected from the N-terminal region of human Ubiquitin.

Isotype: IgG

Application Details

Application Notes:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
IHC-P (10 μg/mL), WB (1:100 - 1:500)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, Sodium azide 0.09 %

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.

Expiry Date: 6 months

Target Details for UBC

Target: UBC (Ubiquitin C (UBC))

Alternative Name: UBC / Ubiquitin C (UBC Products)

Synonyms: HMG20 antibody, 2700054O04Rik antibody, AI194771 antibody, Rps27a antibody, TI-225 antibody, Uba52 antibody, Ubb antibody, ubiquitin C antibody, UBC antibody, Ubc antibody

Background: UBC protein is a polyubiquitin precursor. Conjugation of ubiquitin monomers or polymers can lead to various effects within a cell, depending on the residues to which ubiquitin is conjugated. Ubiquitination has been associated with protein degradation, DNA repair, cell cycle regulation, kinase modification, endocytosis, and regulation of other cell signaling pathways.

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, Toll-Like Receptors Cascades, Synthesis of DNA, EGFR Downregulation, Ubiquitin Proteasome Pathway