MGLUR2 + MGLUR3 antibody (AA 860-875)

Catalog No. ABIN1736902

Product Details anti-MGLUR2 + MGLUR3 Antibody

Target: MGLUR2 + MGLUR3 (GRM2/3) (Glutamate Receptor, Metabotropic 2/3 (GRM2/3))

Binding Specificity: AA 860-875

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MGLUR2 + MGLUR3 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: Reacts with rat mGluR2/3

Cross-Reactivity: Mouse (Murine)

Cross-Reactivity (Details): Predicted react to human and mouse.

Purification: Purified

Immunogen: Synthetic peptide corresponding to residues 860-875 of the rat mGlurR2/3 protein.

Isotype: IgG

Application Details

Application Notes:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
-IHC: 1:10-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, Sodium azide 0.02 %

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Short term storage at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Expiry Date: 6 months

Target Details for MGLUR2 + MGLUR3

Target: MGLUR2 + MGLUR3 (GRM2/3) (Glutamate Receptor, Metabotropic 2/3 (GRM2/3))

Alternative Name: Metabotropic Glutamate Receptor 2/3 (GRM2/3 Products)

Background: Metabotropic glutamate receptors (mGluRs) are G-protein coupled receptors activated by glutamate. Based on sequence similarity, transduction mechanisms and agonist potencies, mGluRs are subdivided into three groups: mGluR1/mGluR5, mGluR2/mGluR3, and mGluR4/mGluR6/mGluR7/mGluR8. mGluRs are widely distributed throughout the nervous system and are expressed by both neurons and glial cells. mGluRs have been suggested to play a variety of functional roles, among which is involvement in synaptic plasticity underlying learning and memory as well as chronic pain.

UniProt: P31421