F12 antibody
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- Target See all F12 Antibodies
- F12 (Coagulation Factor XII (F12))
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Reactivity
- Human
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Host
- Goat
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Clonality
- Polyclonal
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Conjugate
- This F12 antibody is un-conjugated
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Application
- ELISA, Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificity
- Reacts with human F12 / Factor XII
- Cross-Reactivity (Details)
- Specific for Factor XII as demonstrated by immunodiffusion. A single precipitin arc was obtained with normal plasma and no reaction was observed with F. XII-deficient plasma.
- Purification
- Purified
- Immunogen
- Activated human Factor XII (F XIIa) purified from plasma.
- Isotype
- IgG
- Top Product
- Discover our top product F12 Primary Antibody
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- Application Notes
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Working dilution: IHC-P (5 μg/mL)
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- 10 mM HEPES, pH 7.4, 0.15 M NaCl, 50 % glycerol.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Long term: -20°C, Short term: +4°C. Avoid repeat freeze-thaw cycles.
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- Target
- F12 (Coagulation Factor XII (F12))
- Alternative Name
- F12 / Factor XII (F12 Products)
- Synonyms
- HAE3 antibody, HAEX antibody, HAF antibody, FXII antibody, coagulation factor XII antibody, coagulation factor XII (Hageman factor) antibody, F12 antibody
- Background
- Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa.
- Pathways
- Complement System
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