Axin antibody (C-Term)
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- Target See all Axin (AXIN1) Antibodies
- Axin (AXIN1) (Axin 1 (AXIN1))
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Binding Specificity
- C-Term
- Reactivity
- Human, Mouse, Rat, Cow, Dog
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Host
- Goat
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Clonality
- Polyclonal
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Conjugate
- This Axin antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificity
- Reacts with the C-terminus part of human AXIN1
- Cross-Reactivity
- Mouse (Murine), Cow (Bovine), Dog (Canine), Rat (Rattus)
- Cross-Reactivity (Details)
- Cross reacts with bovine, canine, mouse and rat protein. This antibody is expected to recognise both reported isoforms.
- Purification
- Antigen affinity purified
- Immunogen
- Synthetic peptide C-FEEKIIGKVEKVD from the C-terminus of human AXIN1 (NP_003493.1, NP_851393.1). Percent identity with other species by BLAST analysis: Human (100%), Gorilla (100%), Gibbon (100%), Baboon (100%), Monkey (100%), Marmoset (100%)
- Top Product
- Discover our top product AXIN1 Primary Antibody
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- Application Notes
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Working dilution: ELISA (1:128000), IHC-P (3.75 μg/mL)
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- TBS, pH 7.3, BSA 0.5 % , Sodium azide 0.02 %
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Minimize freezing and thawing.
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- Target
- Axin (AXIN1) (Axin 1 (AXIN1))
- Alternative Name
- AXIN1 (AXIN1 Products)
- Synonyms
- AXIN1 antibody, axin antibody, fused antibody, xAxin antibody, LOC100226467 antibody, AXIN antibody, PPP1R49 antibody, AI316800 antibody, Axin antibody, Fu antibody, Kb antibody, Ki antibody, kinky antibody, knobbly antibody, AXIN1-RGS antibody, wu:fi22e03 antibody, wu:fj14c08 antibody, wu:fk11b03 antibody, zgc:109872 antibody, axin 1 antibody, axin 1 S homeolog antibody, axin 1 L homeolog antibody, AXIN1 antibody, axin1.S antibody, axin1.L antibody, Axin1 antibody, axin1 antibody
- Background
- Component of the beta-catenin destruction complex required for regulating CTNNB1 levels through phosphorylation and ubiquitination, and modulating Wnt-signaling. Controls dorsoventral patterning via two opposing effects, down-regulates CTNNB1 to inhibit the Wnt signaling pathway and ventralize embryos, but also dorsalizes embryos by activating a Wnt-independent JNK signaling pathway.
- UniProt
- O15169
- Pathways
- WNT Signaling, Sensory Perception of Sound, Regulation of G-Protein Coupled Receptor Protein Signaling
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