TRF2 antibody (AA 324-500)
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- Target See all TRF2 (TERF2) Antibodies
- TRF2 (TERF2) (Telomeric Repeat Binding Factor 2 (TERF2))
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Binding Specificity
- AA 324-500
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This TRF2 antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (IHC)
- Purpose
- TERF2 Antibody
- Purification
- Purified antibody
- Immunogen
- Purified recombinant fragment of human TERF2 (AA: 324-500) expressed in E. Coli.
- Clone
- 3H6B4
- Isotype
- IgG1
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- Application Notes
- ELISA: 1/10000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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TRF2 controls telomeric nucleosome organization in a cell cycle phase-dependent manner." in: PLoS ONE, Vol. 7, Issue 4, pp. e34386, (2012) (PubMed).
: "Elevated TRF2 in advanced breast cancers with short telomeres." in: Breast cancer research and treatment, Vol. 127, Issue 3, pp. 623-30, (2011) (PubMed).
: "
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TRF2 controls telomeric nucleosome organization in a cell cycle phase-dependent manner." in: PLoS ONE, Vol. 7, Issue 4, pp. e34386, (2012) (PubMed).
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- Target
- TRF2 (TERF2) (Telomeric Repeat Binding Factor 2 (TERF2))
- Alternative Name
- TERF2 (TERF2 Products)
- Synonyms
- TERF2 antibody, TRBF2 antibody, TRF2 antibody, trf2 antibody, telomeric repeat binding factor 2 antibody, telomeric repeat binding factor 2 L homeolog antibody, TERF2 antibody, Terf2 antibody, terf2.L antibody
- Background
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Description: This gene encodes a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic.
Aliases: TRF2, TRBF2
- Molecular Weight
- 55.6kDa
- Gene ID
- 7014
- HGNC
- 7014
- UniProt
- Q15554
- Pathways
- Cell Division Cycle, Telomere Maintenance
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