Syndecan 1 antibody (AA 28-171)

Catalog No. ABIN1724936

Product Details anti-Syndecan 1 Antibody

Target: Syndecan 1 (SDC1)

Binding Specificity: AA 28-171

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Syndecan 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Purpose: SDC1 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human SDC1 (AA: 28-171) expressed in E. Coli.

Clone: 1A3H4

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-Syndecan 1 antibody (ABIN1724936)

Nunez, Siegal, Reddy, Wei: "CD138 (syndecan-1) expression in bone-forming tumors." in: American journal of clinical pathology, Vol. 137, Issue 3, pp. 423-8, (2012) (PubMed).

Karasneh, Ali, Shukla: "An important role for syndecan-1 in herpes simplex virus type-1 induced cell-to-cell fusion and virus spread." in: PLoS ONE, Vol. 6, Issue 9, pp. e25252, (2011) (PubMed).

Target Details for Syndecan 1

Target: Syndecan 1 (SDC1)

Alternative Name: SDC1 (SDC1 Products)

Synonyms: CG10497 antibody, CT27296 antibody, Dmel\\CG10497 antibody, Dsyn antibody, Syd antibody, Syn antibody, dSdc antibody, l(2)10608 antibody, sdc antibody, syd antibody, syn antibody, Syn1 antibody, cd138 antibody, synd1 antibody, xSyn1 antibody, syndecan1 antibody, Syndecan-1 antibody, XSyndecan-1 antibody, SDC1 antibody, CD138 antibody, SDC antibody, SYND1 antibody, syndecan antibody, AA408134 antibody, AA409076 antibody, Sstn antibody, Synd antibody, Synd1 antibody, syn-1 antibody, HSPG antibody, SYNDECA antibody, Syndecan antibody, Syndecan antibody, syndecan 1 antibody, Sdc antibody, sdc1 antibody, SDC1 antibody, Sdc1 antibody

Background:

Description: The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.

Aliases: SDC, CD138, SYND1, syndecan

Molecular Weight: 32.5kDa

Gene ID: 6382

HGNC: 6382

UniProt: P18827

Pathways: Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Lipid Metabolism