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beta-2 Microglobulin antibody (AA 21-100)

Name: beta-2 Microglobulin antibody (AA 21-100)
Brand: antibodies-online
SKU: ABIN1724934
Price: 511.5 USD
Availability: InStock

B2M Reactivity: Human WB, FACS, ELISA, IHC, ICC Host: Mouse Monoclonal 4G5A1 unconjugated

Western blot analysis using B2M mAb against human B2M (AA: 21-100) recombinant protein. (beta-2 Microglobulin antibody (AA 21-100))

Black line: Control Antigen (100 ng), Purple line: Antigen(10 ng), Blue line: Antigen (50 ng), Red line: Antigen (100 ng), (beta-2 Microglobulin antibody (AA 21-100))

ELISA

Flow cytometric analysis of A431 cells using B2M mouse mAb (green) and negative control (red). (beta-2 Microglobulin antibody (AA 21-100))

FACS

Immunofluorescence analysis of Hela cells using B2M mouse mAb (green). (beta-2 Microglobulin antibody (AA 21-100))

Western blot analysis using B2M mAb against HEK293 (1) and B2M (AA: 21-100)-hIgGFc transfected HEK293 (2) cell lysate. (beta-2 Microglobulin antibody (AA 21-100))

Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using B2M mouse mAb with DAB staining. (beta-2 Microglobulin antibody (AA 21-100))

IHC

Immunohistochemical analysis of paraffin-embedded esophageal cancer tissues using B2M mouse mAb with DAB staining. (beta-2 Microglobulin antibody (AA 21-100))

IHC

7 images

(2 references)

Catalog No. ABIN1724934

Datasheet as PDF

Target See all beta-2 Microglobulin (B2M) Antibodies

beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))
Binding Specificity
19

17

15

5

5

5

5

3

2

2

1

1

1

1

1

1
AA 21-100
Reactivity
205

51

30

27

10

4

4

4

3

2

2

1

1

1

1
Human
Host
123

111

9

6

2

1
Mouse
Compatible Secondaries
Clonality
126

125

1
Monoclonal
Conjugate
111

32

25

13

13

7

3

3

3

3

3

3

3

3

3

3

3

3

3

1

1

1

1

1

1

1

1

1

1

1

1
This beta-2 Microglobulin antibody is un-conjugated
Application
127

106

75

66

59

41

40

30

26

18

17

15

13

12

6

4

3

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Purification

purified

Immunogen

Purified recombinant fragment of human B2M (AA: 21-100) expressed in E. coli.

Clone

4G5A1

Isotype

IgG1
anti-beta-2-Microglobulin (B2M) (AA 21-100) antibody
B2M Reactivity: Human WB, FACS, ELISA, IHC Host: Mouse Monoclonal 3G5H8 unconjugated

anti-beta-2-Microglobulin (B2M) (AA 1-119) antibody
B2M Reactivity: Human WB, ELISA, IF, IHC (p), RNAi, PLA Host: Mouse Monoclonal 3F9-2C2 unconjugated

anti-beta-2-Microglobulin (B2M) (AA 22-119) antibody
B2M Reactivity: Mouse WB, IHC, IP, ICC Host: Mouse Monoclonal A2 unconjugated

anti-beta-2-Microglobulin (B2M) (AA 22-119) antibody
B2M Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-beta-2-Microglobulin (B2M) antibody
B2M Reactivity: Human WB, FACS, ELISA, IP, IHC (p), ICC, RIA Host: Mouse Monoclonal B2M-01 unconjugated

anti-beta-2-Microglobulin (B2M) antibody
B2M Reactivity: Human, Non-Human Primate FACS, IHC, IF, StM Host: Mouse Monoclonal rB2M-961 unconjugated Recombinant Antibody

anti-beta-2-Microglobulin (B2M) antibody
B2M Reactivity: Human, Non-Human Primate IHC, StM Host: Mouse Monoclonal B2M-1118 unconjugated

anti-beta-2-Microglobulin (B2M) antibody
B2M Reactivity: Human, Non-Human Primate WB, FACS, IHC, IF, StM Host: Mouse Monoclonal B2M-961 unconjugated

anti-beta-2-Microglobulin (B2M) antibody (Biotin)
B2M Reactivity: Human WB, FACS, ELISA, IP, IHC (p), ICC Host: Mouse Monoclonal B2M-01 Biotin

anti-beta-2-Microglobulin (B2M) antibody
B2M Reactivity: Human, Non-Human Primate FACS, IF, IHC (p) Host: Mouse Monoclonal B2M-961 unconjugated

Application Notes

ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400

Restrictions

For Research Use only
Format

Liquid

Buffer

Purified antibody in PBS with 0.05 % sodium azide.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C/-20 °C

Storage Comment

4°C, -20°C for long term storage
Bernal, Ruiz-Cabello, Concha, Paschen, Garrido: "Implication of the ?2-microglobulin gene in the generation of tumor escape phenotypes." in: Cancer immunology, immunotherapy : CII, Vol. 61, Issue 9, pp. 1359-71, (2012) (PubMed).

Hermansen, Hummelshøj, Lundsgaard, Hornum, Keller, Fleckner, Fox, Poulsen, Jacobsen: "Increased serum ?2-microglobulin is associated with clinical and immunological markers of disease activity in systemic lupus erythematosus patients." in: Lupus, Vol. 21, Issue 10, pp. 1098-104, (2012) (PubMed).
Target

beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

Alternative Name

B2M (B2M Products)

Synonyms

Ly-m11 antibody, beta2-m antibody, beta2m antibody, bwm antibody, wu:fa94c05 antibody, wu:fb10a09 antibody, b2m-W01 antibody, b2m-W03 antibody, b2m-Z01 antibody, b2m-Z02 antibody, b2m-Z03 antibody, B2M antibody, b2m antibody, B2MG antibody, wu:fb66f11 antibody, wu:fj01f08 antibody, zgc:64161 antibody, b-2-m antibody, beta-2-microglobulin antibody, beta-2 microglobulin antibody, beta-2-microglobulin S homeolog antibody, beta-2-microglobulin, like antibody, B2M antibody, B2m antibody, b2m antibody, b2m.S antibody, b2ml antibody

Background

This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia. ,

Molecular Weight

13.7 kDa

Gene ID

567

HGNC

567

Pathways

TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process