NRF2 antibody (AA 356-589)
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- Target See all NRF2 (NFE2L2) Antibodies
- NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))
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Binding Specificity
- AA 356-589
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This NRF2 antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (IHC)
- Purpose
- NFE2L2 Antibody
- Purification
- Purified antibody
- Immunogen
- Purified recombinant fragment of human NFE2L2 (AA: 356-589) expressed in E. Coli.
- Clone
- 1A6G6
- Isotype
- IgG1
- Top Product
- Discover our top product NFE2L2 Primary Antibody
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- Application Notes
- ELISA: 1/10000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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NFE2L2 pathway polymorphisms and lung function decline in chronic obstructive pulmonary disease." in: Physiological genomics, Vol. 44, Issue 15, pp. 754-63, (2012) (PubMed).
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NFE2L2 pathway polymorphisms and lung function decline in chronic obstructive pulmonary disease." in: Physiological genomics, Vol. 44, Issue 15, pp. 754-63, (2012) (PubMed).
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- Target
- NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))
- Alternative Name
- NFE2L2 (NFE2L2 Products)
- Background
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Description: This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters, many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been found for this gene.
Aliases: NRF2
- Molecular Weight
- 67.8kDa
- Gene ID
- 4780
- HGNC
- 4780
- UniProt
- Q16236
- Pathways
- ER-Nucleus Signaling, Negative Regulation of intrinsic apoptotic Signaling
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