MEF2A antibody (AA 391-497)

Catalog No. ABIN1724919

Product Details anti-MEF2A Antibody

Target: MEF2A (Myocyte Enhancer Factor 2A (MEF2A))

Binding Specificity: AA 391-497

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MEF2A antibody is un-conjugated

Application: ELISA

Purpose: MEF2A Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human MEF2A (AA: 391-497) expressed in E. Coli.

Clone: 2F9H2

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-MEF2A antibody (ABIN1724919)

Zhao, Zhao, Peng: "The effects of myocyte enhancer factor 2A gene on the proliferation, migration and phenotype of vascular smooth muscle cells." in: Cell biochemistry and function, Vol. 30, Issue 2, pp. 108-13, (2012) (PubMed).

Guella, Rimoldi, Asselta, Ardissino, Francolini, Martinelli, Girelli, Peyvandi, Tubaro, Merlini, Mannucci, Duga: "Association and functional analyses of MEF2A as a susceptibility gene for premature myocardial infarction and coronary artery disease." in: Circulation. Cardiovascular genetics, Vol. 2, Issue 2, pp. 165-72, (2009) (PubMed).

Target Details for MEF2A

Target: MEF2A (Myocyte Enhancer Factor 2A (MEF2A))

Alternative Name: MEF2A (MEF2A Products)

Synonyms: ADCAD1 antibody, RSRFC4 antibody, RSRFC9 antibody, mef2 antibody, A430079H05Rik antibody, mef2a antibody, wu:fd19d02 antibody, adcad1 antibody, rsrfc4 antibody, rsrfc9 antibody, sl2 antibody, MEF2A antibody, xmef2a antibody, myocyte enhancer factor 2A antibody, myocyte enhancer factor 2aa antibody, myocyte enhancer factor 2a antibody, myocyte-specific enhancer factor 2A antibody, myocyte-specific enhancer factor 2a, putative antibody, myocyte enhancer factor 2A L homeolog antibody, MEF2A antibody, Mef2a antibody, mef2aa antibody, EDI_092490 antibody, EDI_038250 antibody, Smp_161530 antibody, mef2a.L antibody, mef2a antibody, LOC539054 antibody

Background:

Description: The protein encoded by this gene is a DNA-binding transcription factor that activates many muscle-specific, growth factor-induced, and stress-induced genes. The encoded protein can act as a homodimer or as a heterodimer and is involved in several cellular processes, including muscle development, neuronal differentiation, cell growth control, and apoptosis. Defects in this gene could be a cause of autosomal dominant coronary artery disease 1 with myocardial infarction (ADCAD1). Several transcript variants encoding different isoforms have been found for this gene.

Aliases: mef2, ADCAD1, RSRFC4, RSRFC9

Molecular Weight: 54.8kDa

Gene ID: 4205

HGNC: 4205

UniProt: Q02078

Pathways: Neurotrophin Signaling Pathway, Activation of Innate immune Response, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades