ADRP antibody (AA 286-437)

Catalog No. ABIN1724917

Product Details anti-ADRP Antibody

Target: ADRP (PLIN2) (Perilipin 2 (PLIN2))

Binding Specificity: AA 286-437

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ADRP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)

Purpose: PLIN2 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human PLIN2 (AA: 286-437) expressed in E. Coli.

Clone: 2C5H8

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-ADRP antibody (ABIN1724917)

Shepherd, Cocks, Tipton, Ranasinghe, Barker, Burniston, Wagenmakers, Shaw: "Preferential utilization of perilipin 2-associated intramuscular triglycerides during 1 h of moderate-intensity endurance-type exercise." in: Experimental physiology, Vol. 97, Issue 8, pp. 970-80, (2012) (PubMed).

Target Details for ADRP

Target: ADRP (PLIN2) (Perilipin 2 (PLIN2))

Alternative Name: PLIN2 (PLIN2 Products)

Synonyms: ADFP antibody, ADRP antibody, AA407157 antibody, ADPH antibody, Adfp antibody, Adrp antibody, adfp antibody, adrp antibody, fatvg antibody, MGC76047 antibody, adipophilin antibody, PLIN2 antibody, DKFZp469F1012 antibody, perilipin-2 antibody, zgc:110411 antibody, perilipin 2 antibody, perilipin 2 L homeolog antibody, adipophilin antibody, perilipin-2 antibody, PLIN2 antibody, Plin2 antibody, plin2 antibody, plin2.L antibody, LOC100304704 antibody, LOC100380740 antibody

Background:

Description: The protein encoded by this gene belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases. Alternatively spliced transcript variants have been found for this gene.

Aliases: ADFP, ADRP

Molecular Weight: 48kDa

Gene ID: 123

HGNC: 123

UniProt: Q99541

Pathways: Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism