RING1 antibody (AA 79-263)

Catalog No. ABIN1724897

Product Details anti-RING1 Antibody

Target: RING1 (Ring Finger Protein 1 (RING1))

Binding Specificity: AA 79-263

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RING1 antibody is un-conjugated

Application: ELISA, Immunocytochemistry (ICC)

Purpose: Ring1 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human Ring1 (AA: 79-263) expressed in E. Coli.

Clone: 8E8A2

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-RING1 antibody (ABIN1724897)

Vidal: "Role of polycomb proteins Ring1A and Ring1B in the epigenetic regulation of gene expression." in: The International journal of developmental biology, Vol. 53, Issue 2-3, pp. 355-70, (2009) (PubMed).

Target Details for RING1

Target: RING1 (Ring Finger Protein 1 (RING1))

Alternative Name: Ring1 (RING1 Products)

Synonyms: RING1A antibody, RNF1 antibody, Ring1A antibody, bap-1 antibody, bap1 antibody, ding antibody, hipi3 antibody, ring1a antibody, ring1b antibody, ring2 antibody, rnf1 antibody, rnf2-a antibody, ring1 antibody, ring1b-B antibody, rnf2-b antibody, ring finger protein 1 antibody, ring finger protein 1 S homeolog antibody, ring finger protein 1 L homeolog antibody, RING1 antibody, Ring1 antibody, ring1.S antibody, ring1.L antibody

Background:

Description: This gene belongs to the RING finger family, members of which encode proteins characterized by a RING domain, a zinc-binding motif related to the zinc finger domain. The gene product can bind DNA and can act as a transcriptional repressor. It is associated with the multimeric polycomb group protein complex. The gene product interacts with the polycomb group proteins BMI1, EDR1, and CBX4, and colocalizes with these proteins in large nuclear domains. It interacts with the CBX4 protein via its glycine-rich C-terminal domain. The gene maps to the HLA class II region, where it is contiguous with the RING finger genes FABGL and HKE4.

Aliases: RNF1, RING1A

Molecular Weight: 42.4kDa

Gene ID: 6015

HGNC: 6015

UniProt: Q06587