SERPINA7 antibody (AA 168-302)

Catalog No. ABIN1724894

Product Details anti-SERPINA7 Antibody

Target: SERPINA7 (Serpin Family A Member 7 (SERPINA7))

Binding Specificity: AA 168-302

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SERPINA7 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

Purpose: SERPINA7 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human SERPINA7 (AA: 168-302) expressed in E. Coli.

Clone: 5B11E9

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-SERPINA7 antibody (ABIN1724894)

Yan, Yan, Ou: "Human thyroxine binding globulin (TBG) promoter directs efficient and sustaining transgene expression in liver-specific pattern." in: Gene, Vol. 506, Issue 2, pp. 289-94, (2012) (PubMed).

Duhan, Patston: "Explanation for the high heat stability of thyroxine binding globulin-Chicago." in: Endocrine regulations, Vol. 44, Issue 2, pp. 43-7, (2010) (PubMed).

Target Details for SERPINA7

Target: SERPINA7 (Serpin Family A Member 7 (SERPINA7))

Alternative Name: SERPINA7 (SERPINA7 Products)

Background:

Description: There are three proteins including thyroxine-binding globulin (TBG), transthyretin and albumin responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3) in the bloodstream. This gene encodes the major thyroid hormone transport protein, TBG, in serum. It belongs to the serpin family in genomics, but the protein has no inhibitory function like many other members of the serpin family. Mutations in this gene result in TGB deficiency, which has been classified as partial deficiency, complete deficiency, and excess, based on the level of serum TBG. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.

Aliases: TBG

Molecular Weight: 46.3kDa

Gene ID: 6906

HGNC: 6906

UniProt: P05543

Pathways: Hormone Transport