SYCP3 antibody (AA 27-128)

Catalog No. ABIN1724891

Product Details anti-SYCP3 Antibody

Target: SYCP3 (Synaptonemal Complex Protein 3 (SYCP3))

Binding Specificity: AA 27-128

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SYCP3 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Purpose: SYCP3 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human SYCP3 (AA: 27-128) expressed in E. Coli.

Clone: 6F9B6

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-SYCP3 antibody (ABIN1724891)

Chung, Kitano, Takikita, Cho, Noh, Kim, Ylaya, Hanaoka, Fukuoka, Hewitt: "Synaptonemal complex protein 3 as a novel prognostic marker in early stage non-small cell lung cancer." in: Human pathology, Vol. 44, Issue 4, pp. 472-9, (2013) (PubMed).

Alsheimer, Baier, Schramm, Schütz, Benavente: "Synaptonemal complex protein SYCP3 exists in two isoforms showing different conservation in mammalian evolution." in: Cytogenetic and genome research, Vol. 128, Issue 1-3, pp. 162-8, (2010) (PubMed).

Target Details for SYCP3

Target: SYCP3 (Synaptonemal Complex Protein 3 (SYCP3))

Alternative Name: SYCP3 (SYCP3 Products)

Synonyms: Cor1 antibody, Scp3 antibody, COR1 antibody, SCP3 antibody, SPGF4 antibody, RNASCP3 antibody, SYCP3 antibody, sycp3 antibody, MGC146429 antibody, scp3 antibody, SCP-3 antibody, synaptonemal complex protein 3 antibody, synaptonemal complex protein 3 L homeolog antibody, Sycp3 antibody, SYCP3 antibody, sycp3 antibody, scp3 antibody, sycp3.L antibody

Background:

Description: This gene encodes an essential structural component of the synaptonemal complex. This complex is involved in synapsis, recombination and segregation of meiotic chromosomes. Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females. Alternate splicing results in multiple transcript variants that encode the same protein.

Aliases: COR1, SCP3, SPGF4

Molecular Weight: 27.7kDa

Gene ID: 50511

HGNC: 50511

UniProt: Q8IZU3