ZEB1 antibody (AA 967-1108)

Catalog No. ABIN1724885

Product Details anti-ZEB1 Antibody

Target: ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))

Binding Specificity: AA 967-1108

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ZEB1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Purpose: ZEB1 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human ZEB1 (AA: 967-1108) expressed in E. Coli.

Clone: 2A8A6

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-ZEB1 antibody (ABIN1724885)

Liu, Yan, Liu, Zhou, Liu, Pang, Cao, Liu, Wang, Liu, Zhang: "Lentivirus-delivered ZEB-1 small interfering RNA inhibits lung adenocarcinoma cell growth in vitro and in vivo." in: Journal of cancer research and clinical oncology, Vol. 138, Issue 8, pp. 1329-38, (2012) (PubMed).

Jia, Liu, Kong, Li: "Overexpression of ZEB1 associated with metastasis and invasion in patients with gastric carcinoma." in: Molecular and cellular biochemistry, Vol. 366, Issue 1-2, pp. 223-9, (2012) (PubMed).

Target Details for ZEB1

Target: ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))

Alternative Name: ZEB1 (ZEB1 Products)

Synonyms: ZFH/[d]EF1 antibody, kheper antibody, zeb1 antibody, zfhx1 antibody, bzp antibody, zeb antibody, tcf8 antibody, areb6 antibody, nil2a antibody, zfhep antibody, nil-2a antibody, zfhx1a antibody, nil-2-a antibody, MGC97552 antibody, TCF8 antibody, AREB6 antibody, BZP antibody, DELTAEF1 antibody, FECD6 antibody, NIL2A antibody, PPCD3 antibody, ZFHEP antibody, ZFHX1A antibody, 3110032K11Rik antibody, MEB1 antibody, Nil2 antibody, TCF-8 antibody, Tcf18 antibody, Tcf8 antibody, Tw antibody, ZEB antibody, Zfhep antibody, Zfhx1a antibody, Zfx1a antibody, Zfx1ha antibody, [delta]EF1 antibody, deltaEF1 antibody, deltaef1 antibody, fecd6 antibody, zinc finger E-box binding homeobox 1b antibody, zinc finger E-box binding homeobox 1 antibody, zinc finger E-box binding homeobox 1 S homeolog antibody, zeb1b antibody, zeb1 antibody, ZEB1 antibody, Zeb1 antibody, zeb1.S antibody

Background:

Description: This gene encodes a zinc finger transcription factor. The encoded protein likely plays a role in transcriptional repression of interleukin 2. Mutations in this gene have been associated with posterior polymorphous corneal dystrophy-3 and late-onset Fuchs endothelial corneal dystrophy. Alternatively spliced transcript variants encoding different isoforms have been described.

Aliases: BZP, TCF8, AREB6, FECD6, NIL2A, PPCD3, ZFHEP, ZFHX1A, DELTAEF1

Molecular Weight: 124kDa

Gene ID: 6935

HGNC: 6935

UniProt: P37275

Pathways: Regulation of Muscle Cell Differentiation