PHC1 antibody (AA 758-1004)

Catalog No. ABIN1724838

Product Details anti-PHC1 Antibody

Target: PHC1 (Polyhomeotic-Like 1 (PHC1))

Binding Specificity: AA 758-1004

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PHC1 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Purpose: PHC1 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human PHC1 (AA: 758-1004) expressed in E. Coli.

Clone: 1F3F3

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-PHC1 antibody (ABIN1724838)

Boyer, Plath, Zeitlinger, Brambrink, Medeiros, Lee, Levine, Wernig, Tajonar, Ray, Bell, Otte, Vidal, Gifford, Young, Jaenisch: "Polycomb complexes repress developmental regulators in murine embryonic stem cells." in: Nature, Vol. 441, Issue 7091, pp. 349-53, (2006) (PubMed).

Target Details for PHC1

Target: PHC1 (Polyhomeotic-Like 1 (PHC1))

Alternative Name: PHC1 (PHC1 Products)

Synonyms: EDR1 antibody, HPH1 antibody, RAE28 antibody, AW557034 antibody, Edr antibody, Edr1 antibody, Mph1 antibody, Rae-28 antibody, rae28 antibody, polyhomeotic homolog 1 antibody, polyhomeotic-like 1 (Drosophila) antibody, Phc1 antibody, PHC1 antibody

Background:

Description: This gene is a homolog of the Drosophila polyhomeotic gene, which is a member of the Polycomb group of genes. The gene product is a component of a multimeric protein complex that contains EDR2 and the vertebrate Polycomb protein BMH1. The gene product, the EDR2 protein, and the Drosophila polyhomeotic protein share 2 highly conserved domains, named homology domains I and II. These domains are involved in protein-protein interactions and may mediate heterodimerization of the protein encoded by this gene and the EDR2 protein.

Aliases: EDR1, HPH1, RAE28

Molecular Weight: 105.5kDa

Gene ID: 1911

HGNC: 1911

UniProt: P78364