SQSTM1 antibody (AA 232-356)
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- Target See all SQSTM1 Antibodies
- SQSTM1 (Sequestosome 1 (SQSTM1))
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Binding Specificity
- AA 232-356
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This SQSTM1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)
- Purification
- Purified
- Immunogen
- Purified recombinant fragment of human SQSTM1 (AA: 232-356) expressed in E. Coli.
- Clone
- 5H7E2
- Isotype
- IgG1
- Top Product
- Discover our top product SQSTM1 Primary Antibody
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- Application Notes
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Recommended Dilution:
ELISA: 1/10000
WB: 1/500 - 1/2000
IHC: 1/200 - 1/1000
FCM: 1/200 - 1/400 - Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.05 % sodium azide and 0.5 % protein stabilizer
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C or at -20 °C for long term.
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Accumulation of p62/SQSTM1 is associated with poor prognosis in patients with lung adenocarcinoma." in: Cancer science, Vol. 103, Issue 4, pp. 760-6, (2012) (PubMed).
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Accumulation of p62/SQSTM1 is associated with poor prognosis in patients with lung adenocarcinoma." in: Cancer science, Vol. 103, Issue 4, pp. 760-6, (2012) (PubMed).
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- Target
- SQSTM1 (Sequestosome 1 (SQSTM1))
- Alternative Name
- SQSTM1 (SQSTM1 Products)
- Synonyms
- SQSTM1 antibody, sqstm1 antibody, MGC79491 antibody, A170 antibody, OSIL antibody, PDB3 antibody, ZIP3 antibody, p60 antibody, p62 antibody, p62B antibody, OSF-6 antibody, Osi antibody, STAP antibody, ZIP antibody, sb:cb621 antibody, zgc:85784 antibody, sequestosome 1 antibody, sequestosome 1 L homeolog antibody, SQSTM1 antibody, sqstm1 antibody, Sqstm1 antibody, sqstm1.L antibody
- Background
- This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.
- Molecular Weight
- 47.7 kDa
- Gene ID
- 8878
- HGNC
- 8878
- Pathways
- NF-kappaB Signaling, Neurotrophin Signaling Pathway, Autophagy
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