NrCAM antibody (AA 1192-1255)

Catalog No. ABIN1724829

Product Details anti-NrCAM Antibody

Target: NrCAM (NRCAM) (Neuronal Cell Adhesion Molecule (NRCAM))

Binding Specificity: AA 1192-1255

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This NrCAM antibody is un-conjugated

Application: ELISA, Immunocytochemistry (ICC)

Purpose: NRCAM Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human NRCAM (AA: 1192-1255) expressed in E. Coli.

Clone: 7D8C5

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

ICC: 1/50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-NrCAM antibody (ABIN1724829)

Kim, Kim, Kim, Kwack, Park, Kim, Kim, Ban, Chung: "Association between neuronal cell adhesion molecule (NRCAM) single nucleotide polymorphisms and schizophrenia in a Korean population." in: Psychiatry and clinical neurosciences, Vol. 63, Issue 1, pp. 123-4, (2009) (PubMed).

Target Details for NrCAM

Target: NrCAM (NRCAM) (Neuronal Cell Adhesion Molecule (NRCAM))

Alternative Name: NRCAM (NRCAM Products)

Synonyms: CD56 antibody, MSK39 antibody, NCAM antibody, Bravo antibody, C030017F07Rik antibody, C130076O07Rik antibody, mKIAA0343 antibody, NRCAM antibody, si:dkey-240a12.1 antibody, Nr-CAM antibody, neural cell adhesion molecule 1 antibody, neuronal cell adhesion molecule antibody, neuronal cell adhesion molecule L homeolog antibody, neuronal cell adhesion molecule a antibody, NCAM1 antibody, NRCAM antibody, Nrcam antibody, nrcam.L antibody, nrcama antibody, nrcam antibody

Background:

Description: Cell adhesion molecules (CAMs) are members of the immunoglobulin superfamily. This gene encodes a neuronal cell adhesion molecule with multiple immunoglobulin-like C2-type domains and fibronectin type-III domains. This ankyrin-binding protein is involved in neuron-neuron adhesion and promotes directional signaling during axonal cone growth. This gene is also expressed in non-neural tissues and may play a general role in cell-cell communication via signaling from its intracellular domain to the actin cytoskeleton during directional cell migration. Allelic variants of this gene have been associated with autism and addiction vulnerability. Alternative splicing results in multiple transcript variants encoding different isoforms.

Aliases: NRCAM

Molecular Weight: 144kDa

Gene ID: 4897

HGNC: 4897

UniProt: Q92823

Pathways: Regulation of Cell Size