Integrin Alpha2b antibody (AA 45-149)
(2 references)-
- Target See all Integrin Alpha2b (CD41) Antibodies
- Integrin Alpha2b (CD41)
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Binding Specificity
- AA 45-149
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Integrin Alpha2b antibody is un-conjugated
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Application
- Flow Cytometry (FACS), ELISA, Immunohistochemistry (IHC)
- Purpose
- ITGA2B Antibody
- Purification
- Ascitic fluid
- Immunogen
- Purified recombinant fragment of human ITGA2B (AA: 45-149) expressed in E. Coli.
- Clone
- 2E10C9
- Isotype
- IgG1
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anti-Integrin Alpha2b (CD41) (AA 351-450) antibody
CD41 Reactivity: Human, Rat FACS, WB, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) Host: Rabbit Polyclonal unconjugated
anti-Integrin Alpha2b (CD41) antibodyCD41 Reactivity: Mouse FACS, ELISA, IHC (fro), IP, IHC (p) Host: Rat Monoclonal MWReg30 unconjugated
anti-Integrin Alpha2b (CD41) antibodyCD41 Reactivity: Mouse FACS, ELISA, IHC (fro), IP, IHC (p), Func Host: Rat Monoclonal MWReg30 unconjugated
anti-Integrin Alpha2b (CD41) antibodyCD41 Reactivity: Human, Non-Human Primate FACS, IHC (fro) Host: Mouse Monoclonal HIP2 unconjugated
anti-Integrin Alpha2b (CD41) antibody (Biotin)CD41 Reactivity: Human FACS Host: Mouse Monoclonal MEM-06 Biotin
anti-Integrin Alpha2b (CD41) antibody (FITC)CD41 Reactivity: Human FACS Host: Mouse Monoclonal MEM-06 FITC
anti-Integrin Alpha2b (CD41) (AA 677-711), (C-Term) antibodyCD41 Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Integrin Alpha2b (CD41) antibodyCD41 Reactivity: Human, Non-Human Primate FACS, IHC (fro) Host: Mouse Monoclonal HIP8 unconjugated
anti-Integrin Alpha2b (CD41) (AA 639-887) antibodyCD41 Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Integrin Alpha2b (CD41) antibody (PE)CD41 Reactivity: Mouse FACS Host: Rat Monoclonal MWReg30 PE
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- Application Notes
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Novel and recurrent mutations of ITGA2B and ITGB3 genes in Korean patients with Glanzmann thrombasthenia." in: Pediatric blood & cancer, Vol. 59, Issue 2, pp. 335-8, (2012) (PubMed).
: "Glanzmann thrombasthenia: a review of ITGA2B and ITGB3 defects with emphasis on variants, phenotypic variability, and mouse models." in: Blood, Vol. 118, Issue 23, pp. 5996-6005, (2011) (PubMed).
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: "Novel and recurrent mutations of ITGA2B and ITGB3 genes in Korean patients with Glanzmann thrombasthenia." in: Pediatric blood & cancer, Vol. 59, Issue 2, pp. 335-8, (2012) (PubMed).
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- Target
- Integrin Alpha2b (CD41)
- Alternative Name
- ITGA2B (CD41 Products)
- Background
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Description: ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.
Aliases: GT, GTA, CD41, GP2B, HPA3, CD41B, GPIIb, BDPLT2
- Molecular Weight
- 113.4kDa
- Gene ID
- 3674
- HGNC
- 3674
- UniProt
- P08514
- Pathways
- Integrin Complex
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