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TP53BP1 antibody (AA 574-773)

Name: TP53BP1 antibody (AA 574-773)
Brand: antibodies-online
SKU: ABIN1724820
Price: 511.5 USD
Availability: InStock

TP53BP1 Reactivity: Human WB, IHC, ELISA, FACS Host: Mouse Monoclonal 6B3E10 unconjugated

Immunohistochemical analysis of paraffin-embedded endometrial cancer tissues using TP53BP1 mouse mAb with DAB staining. (TP53BP1 antibody (AA 574-773))

IHC

Western blot analysis using TP53BP1 mAb against human TP53BP1 recombinant protein. (TP53BP1 antibody (AA 574-773))

Black line: Control Antigen (100 ng), Purple line: Antigen(10 ng), Blue line: Antigen (50 ng), Red line: Antigen (100 ng), (TP53BP1 antibody (AA 574-773))

ELISA

Flow cytometric analysis of HepG2 cells using TP53BP1 mouse mAb (green) and negative control (purple). (TP53BP1 antibody (AA 574-773))

FACS

Western blot analysis using TP53BP1 mAb against HEK293 (1) and TP53BP1 (AA: 574-773)-hIgGFc transfected HEK293 (2) cell lysate. (TP53BP1 antibody (AA 574-773))

Immunohistochemical analysis of paraffin-embedded colon cancer tissues using TP53BP1 mouse mAb with DAB staining. (TP53BP1 antibody (AA 574-773))

IHC

6 images

(2 references)

Catalog No. ABIN1724820

Datasheet as PDF

Target See all TP53BP1 Antibodies

TP53BP1 (Tumor Protein P53 Binding Protein 1 (TP53BP1))
Binding Specificity
32

21

15

11

8

6

4

4

3

3

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 574-773
Reactivity
103

63

61

7

4

4

4

3

2

2

1

1

1
Human
Host
108

7

2

1
Mouse
Compatible Secondaries
Clonality
102

16
Monoclonal
Conjugate
57

5

5

5

5

5

5

5

2

2

2

2

2

2

2

2

2

2

2

2

2
This TP53BP1 antibody is un-conjugated
Application
43

29

27

27

25

18

17

12

10

7

5

4

4

2

2

1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Purpose

TP53BP1 Antibody

Purification

Ascitic fluid

Immunogen

Purified recombinant fragment of human TP53BP1 (AA: 574-773) expressed in E. Coli.

Clone

6B3E10

Isotype

IgG1
anti-Tumor Protein P53 Binding Protein 1 (TP53BP1) (N-Term) antibody
KO Validated TP53BP1 Reactivity: Human WB, IF, ICC, IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated

anti-Tumor Protein P53 Binding Protein 1 (TP53BP1) (AA 1955-1972), (C-Term) antibody
TP53BP1 Reactivity: Human, Mouse, Rat WB, ICC, IHC (p) Host: Rabbit Polyclonal unconjugated

anti-Tumor Protein P53 Binding Protein 1 (TP53BP1) (pSer25), (pSer29) antibody
TP53BP1 Reactivity: Human, Mouse, Rat ELISA, ICC, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated

anti-Tumor Protein P53 Binding Protein 1 (TP53BP1) (N-Term) antibody
TP53BP1 Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-Tumor Protein P53 Binding Protein 1 (TP53BP1) (AA 1763-1977) antibody
TP53BP1 Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated

anti-Tumor Protein P53 Binding Protein 1 (TP53BP1) (pThr543) antibody
TP53BP1 Reactivity: Human, Monkey WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-Tumor Protein P53 Binding Protein 1 (TP53BP1) (N-Term) antibody
TP53BP1 Reactivity: Human, Mouse, Rat WB, IHC, IF, IC Host: Rabbit Polyclonal unconjugated

anti-Tumor Protein P53 Binding Protein 1 (TP53BP1) (AA 1724-1964) antibody
TP53BP1 Reactivity: Human WB, IHC, ICC, IP Host: Rabbit Polyclonal unconjugated

anti-Tumor Protein P53 Binding Protein 1 (TP53BP1) (AA 1758-1972) antibody
TP53BP1 Reactivity: Human IHC, ELISA Host: Rabbit Polyclonal unconjugated

anti-Tumor Protein P53 Binding Protein 1 (TP53BP1) (Tyr217) antibody
TP53BP1 Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated

Application Notes

ELISA: 1/10000
FCM: 1/200 - 1/400

Restrictions

For Research Use only
Format

Liquid

Buffer

Ascitic fluid containing 0.03 % sodium azide.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C,-20 °C

Storage Comment

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Nakada, Yonamine, Matsuo: "RNF8 regulates assembly of RAD51 at DNA double-strand breaks in the absence of BRCA1 and 53BP1." in: Cancer research, Vol. 72, Issue 19, pp. 4974-83, (2012) (PubMed).

Mok, Henderson: "The in vivo dynamic interplay of MDC1 and 53BP1 at DNA damage-induced nuclear foci." in: The international journal of biochemistry & cell biology, Vol. 44, Issue 9, pp. 1398-409, (2012) (PubMed).
Target

TP53BP1 (Tumor Protein P53 Binding Protein 1 (TP53BP1))

Alternative Name

TP53BP1 (TP53BP1 Products)

Synonyms

TP53BP1 antibody, MGC160112 antibody, 53BP1 antibody, Tp53bp1 antibody, m53BP1 antibody, p202 antibody, Trp53bp1 antibody, tumor protein p53 binding protein 1 antibody, tumor suppressor p53-binding protein 1 antibody, tumor protein p53 binding protein 1 (predicted), 5 prime antibody, transformation related protein 53 binding protein 1 antibody, TP53BP1 antibody, tp53bp1 antibody, LOC100550605 antibody, Trp53bp1 antibody, Tp53bp1 antibody

Background

Description: T protein p53 binding protein 1 may have a role in checkpoint signaling during mitosis,enhance TP53-mediated transcriptional activation and play a role in the response to DNA damage.
Aliases: p202, 53BP1

Molecular Weight

213.6kDa

Gene ID

7158

HGNC

7158

UniProt

Q12888

Pathways

DNA Damage Repair